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NCT04659317 · ClinicalTrials.gov registry record · Phase 3
Opioid-Free Orthopaedics
A Phase 3 study of Pain and Pain, Postoperative, sponsored by Emory University.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 80
- Enrollment target
- 3
- Study locations
NCT04659317: Recruiting Phase 3 study of Pain and Pain, Postoperative, sponsored by Emory University.
NCT04659317 is a Phase 3 study of Pain and Pain, Postoperative that is actively recruiting participants, run by Emory University. The registered enrollment target is 80 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (74% lower). The trial reports 3 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04659317, a Phase 3 study of Pain and Pain, Postoperative, is actively recruiting participants, sponsored by Emory University.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 80 participants
- Enrollment target
- 3
- Study locations
Study Summary
The goal of this investigation is to compare effectiveness of this multimodal regimen at controlling postoperative pain with and without the use of opioid medications.
Primary Outcome
The investigators will assess patient postoperative pain utilizing a visual analog scale (VAS) for the first 14 days postoperatively. They will also assess pain at each postoperative visit after at 6 weeks, 3 months, 6 months, 12 months, 24 months, and 60 months. This scale will assess pain at 3 different timepoints throughout the day defined as morning, afternoon, and evening. The pain scale will range from 0-10 with 10 being a worse outcome quantifying the highest pain rating.
Conditions Studied
Interventions
- DRUG Placebo oral tablet
- DRUG Oxycodone 5 mg Oral Tablet
Study Locations (3)
Georgia
- The Emory Clinic - Atlanta
- Emory University Hospital - Atlanta
- Emory Orthopedic and Spine Hospital - Tucker
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2020-12-11 |
| Est. Completion | 2028-12 |
| Phase | Phase 3 |
What NCT04659317 shows while recruiting
NCT04659317 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 304-participant average among 374 other Pain trials with a reported enrollment target (74% lower).
The record links to 2 conditions, with Pain appearing as the primary indexed condition, and to 2 interventions - of which Placebo oral tablet is the first listed.
NCT04659317 reports a single indexed study location in Georgia.
Frequently Asked Questions
What is clinical trial NCT04659317 about?
NCT04659317 is a clinical study titled "Opioid-Free Orthopaedics". The goal of this investigation is to compare effectiveness of this multimodal regimen at controlling postoperative pain with and without the use of opioid medications.
What is the current status of trial NCT04659317?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 80 participants. The study started on 2020-12-11. Estimated completion is 2028-12.
What conditions does trial NCT04659317 study?
This clinical trial studies the following conditions: Pain, Pain, Postoperative.
What interventions are being tested in trial NCT04659317?
The interventions under investigation include: Placebo oral tablet (DRUG), Oxycodone 5 mg Oral Tablet (DRUG).
Who is sponsoring clinical trial NCT04659317?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04659317 being conducted?
This trial has 3 study locations across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04659317's enrollment target sits among peer trials
80 193rd of 374 higher than 171 of 374 other Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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