Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Pain and Opioids: Integrated Treatment In Veterans
NCT04648228 · View on ClinicalTrials.gov ↗
Study Summary
This trial will recruit veterans with chronic pain (N = 160) who are prescribed buprenorphine for the treatment of opioid use disorder (OUD). We seek to: (1) examine the efficacy of an integrated treatment to reduce pain interference (Acceptance and Commitment Therapy and Mindfulness-Based Relapse Prevention \[ACT + MBRP\]) compared to an education control (EC) consisting of a protocol-based series of education sessions concerning chronic pain, opioids, and buprenorphine use and (2) examine how theoretically-relevant treatment mechanisms of pain acceptance, engagement in values-based action, and opioid craving are related to treatment outcomes. Interventions will be delivered via the VA Video Connect telehealth modality.
Conditions Studied
Interventions
- BEHAVIORAL ACT+MBRP
- BEHAVIORAL Education control
Study Locations (4)
New Mexico
- New Mexico VA Healthcare System — Albuquerque
- University of New Mexico — Albuquerque
California
- San Francisco VA Health Care System — San Francisco
Washington
- Puget Sound VA Healthcare System — Tacoma
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 157 participants |
| Start Date | 2021-07-01 |
| Est. Completion | 2026-08-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04648228
The ClinicalTrials.gov registry entry for NCT04648228 describes a study currently listed as active not recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 157 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of New Mexi, which has 107 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 3 conditions, with Chronic Pain appearing as the primary indexed condition, and to 2 interventions — of which ACT+MBRP is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04648228 reports 4 study locations spanning 3 distinct geographic areas — top geographies include New Mexico, California, Washington. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04648228 about?
NCT04648228 is a clinical study titled "Pain and Opioids: Integrated Treatment In Veterans". This trial will recruit veterans with chronic pain (N = 160) who are prescribed buprenorphine for the treatment of opioid use disorder (OUD). We seek to: (1) examine the efficacy of an integrated treatment to reduce pain interference (Acceptance and Commitment Therapy and Mindfulness-Based Relapse P...
What is the current status of trial NCT04648228?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 157 participants. The study started on 2021-07-01. Estimated completion is 2026-08-31.
What conditions does trial NCT04648228 study?
This clinical trial studies the following conditions: Chronic Pain, Opioid-use Disorder, Opioids; Harmful Use. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04648228?
The interventions under investigation include: ACT+MBRP (BEHAVIORAL), Education control (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04648228?
This trial is sponsored by University of New Mexi, which has 107 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04648228 being conducted?
This trial has 4 study locations across California, New Mexico, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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