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NCT04575844 · ClinicalTrials.gov registry record · Phase 4
Effects of Exercise and GLP-1 Agonism on Muscle Microvascular Perfusion and Insulin Action in Adults With Metabolic Syndrome
A Phase 4 study of Metabolic Syndrome, sponsored by University of Virginia.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT04575844 is a Phase 4 study of Metabolic Syndrome that is actively recruiting participants, run by University of Virginia. The registered enrollment target is 80 participants, below the 1,204-participant average among 102 other Metabolic Syndrome trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04575844, a Phase 4 study of Metabolic Syndrome, is actively recruiting participants, sponsored by University of Virginia.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary objective of this study is to examine whether exercise training alone, liraglutide treatment alone or exercise training plus liraglutide treatment increases cardiac and skeletal muscle microvascular blood volume, improves vascular function of the conduit vessels, and enhances insulin's metabolic action in humans with Metabolic Syndrome. Subjects will be randomized to one of the 4 groups: control, exercise training, liraglutide treatment, and exercise + liraglutide. They will be studied at the baseline and then after 24 weeks of intervention.
Conditions Studied
Interventions
- DRUG Liraglutide
- OTHER Exercise training
- DRUG Liraglutide + Exercise training
Study Locations (1)
Virginia
- University of Virginia - Charlottesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2020-11-01 |
| Est. Completion | 2026-04-30 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04575844
The ClinicalTrials.gov registry entry for NCT04575844 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,204-participant average among 102 other Metabolic Syndrome trials with a reported enrollment target (93% lower). The listed sponsor is University of Virginia, which has 449 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Metabolic Syndrome appearing as the primary indexed condition, and to 3 interventions - of which Liraglutide is the first listed.
NCT04575844 reports 1 study location spanning 1 distinct geographic area - top geographies include Virginia.
Frequently Asked Questions
What is clinical trial NCT04575844 about?
NCT04575844 is a clinical study titled "Effects of Exercise and GLP-1 Agonism on Muscle Microvascular Perfusion and Insulin Action in Adults With Metabolic Syndrome". The primary objective of this study is to examine whether exercise training alone, liraglutide treatment alone or exercise training plus liraglutide treatment increases cardiac and skeletal muscle microvascular blood volume, improves vascular function of the conduit vessels, and enhances insulin's m...
What is the current status of trial NCT04575844?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 80 participants. The study started on 2020-11-01. Estimated completion is 2026-04-30.
What conditions does trial NCT04575844 study?
This clinical trial studies the following conditions: Metabolic Syndrome.
What interventions are being tested in trial NCT04575844?
The interventions under investigation include: Liraglutide (DRUG), Exercise training (OTHER), Liraglutide + Exercise training (DRUG).
Who is sponsoring clinical trial NCT04575844?
This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04575844 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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