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NCT04575844 · ClinicalTrials.gov registry record · Phase 4
Effects of Exercise and GLP-1 Agonism on Muscle Microvascular Perfusion and Insulin Action in Adults With Metabolic Syndrome
A Phase 4 study of Metabolic Syndrome, sponsored by University of Virginia.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT04575844: Recruiting Phase 4 study of Metabolic Syndrome, sponsored by University of Virginia.
NCT04575844 is a Phase 4 study of Metabolic Syndrome that is actively recruiting participants, run by University of Virginia. The registered enrollment target is 80 participants, below the 1,204-participant average among 102 other Metabolic Syndrome trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04575844, a Phase 4 study of Metabolic Syndrome, is actively recruiting participants, sponsored by University of Virginia.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary objective of this study is to examine whether exercise training alone, liraglutide treatment alone or exercise training plus liraglutide treatment increases cardiac and skeletal muscle microvascular blood volume, improves vascular function of the conduit vessels, and enhances insulin's metabolic action in humans with Metabolic Syndrome. Subjects will be randomized to one of the 4 groups: control, exercise training, liraglutide treatment, and exercise + liraglutide. They will be studied at the baseline and then after 24 weeks of intervention.
Primary Outcome
measured at baseline and 24 weeks
Conditions Studied
Interventions
- DRUG Liraglutide
- OTHER Exercise training
- DRUG Liraglutide + Exercise training
Study Locations (1)
Virginia
- University of Virginia - Charlottesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2020-11-01 |
| Est. Completion | 2026-04-30 |
| Phase | Phase 4 |
What NCT04575844 shows while recruiting
NCT04575844 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 1,204-participant average among 102 other Metabolic Syndrome trials with a reported enrollment target (93% lower).
The record links to 1 condition, with Metabolic Syndrome appearing as the primary indexed condition, and to 3 interventions - of which Liraglutide is the first listed.
NCT04575844 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT04575844 about?
NCT04575844 is a clinical study titled "Effects of Exercise and GLP-1 Agonism on Muscle Microvascular Perfusion and Insulin Action in Adults With Metabolic Syndrome". The primary objective of this study is to examine whether exercise training alone, liraglutide treatment alone or exercise training plus liraglutide treatment increases cardiac and skeletal muscle microvascular blood volume, improves vascular function of the conduit vessels, and enhances insulin's m...
What is the current status of trial NCT04575844?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 80 participants. The study started on 2020-11-01. Estimated completion is 2026-04-30.
What conditions does trial NCT04575844 study?
This clinical trial studies the following conditions: Metabolic Syndrome.
What interventions are being tested in trial NCT04575844?
The interventions under investigation include: Liraglutide (DRUG), Exercise training (OTHER), Liraglutide + Exercise training (DRUG).
Who is sponsoring clinical trial NCT04575844?
This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04575844 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Metabolic Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04575844's enrollment target sits among peer trials
80 40th of 102 higher than 60 of 102 other Metabolic Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Metabolic Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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