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NCT04550676 · ClinicalTrials.gov registry record · NA
High-Intensity Exercise to Attenuate Limitations and Train Habits in Older Adults With HIV
A NA study of HIV and Fatigue, sponsored by University of Colorado, Denver.
- Active
- Registry status
- NA
- Development phase
- 118
- Enrollment target
- 2
- Study locations
NCT04550676: Active NA study of HIV and Fatigue, sponsored by University of Colorado, Denver.
NCT04550676 is a NA study of HIV and Fatigue that is active but no longer recruiting, run by University of Colorado, Denver. The registered enrollment target is 118 participants, below the 439-participant average among 303 other HIV trials with a reported enrollment target (73% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04550676, a NA study of HIV and Fatigue, is active but no longer recruiting, sponsored by University of Colorado, Denver.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 118 participants
- Enrollment target
- 2
- Study locations
Study Summary
This is a multi-site, randomized, single-blind (researchers), active treatment concurrent control trial with individuals aged 50-80 living with HIV who experience fatigue and live a sedentary lifestyle. The overall goals of this proposal are to determine whether high-intensity interval training (HIIT) can overcome physical function impairments and increased fatigue (Aim 1) and impairments in mitochondrial bioenergetics of older people with HIV (PWH) to a greater extent than continuous moderate-intensity exercise (CME) (Aim 2). The investigators further seek to determine whether a biobehavioral coaching intervention following either HIIT or CME can promote long-term adherence to physical activity (Aim 3), a crucial component of the sustainability of the intervention. This study will enroll 100 participants in Aurora, Colorado and Seattle, Washington. Data collection will occur at each visit, with baseline data collected at the initial visit. A 3-month follow-up will be conducted over the phone from the date of the final visit. The initial enrollment goal of 100 was increased to 120 in 2023 to facilitate a larger number of participants with key secondary outcomes.
Primary Outcome
400-m walk time is a continuous measure of the total time required to complete a 400-m walking course. Lower values indicate a faster walking speed.
Conditions Studied
Interventions
- BEHAVIORAL HIIT (intervention)
- BEHAVIORAL CME (active control)
Study Locations (2)
Colorado
- University of Colorado - Anschutz Medical Campus - Aurora
Washington
- University of Washington - Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 118 participants |
| Start Date | 2021-04-02 |
| Est. Completion | 2025-11-24 |
| Phase | NA |
What the registry record for NCT04550676 still lists
NCT04550676 is an interventional study that assigns participants to a tested intervention. The registered 118 participants enrollment target is mid-sized for trials with a published cap, below the 439-participant average among 303 other HIV trials with a reported enrollment target (73% lower).
The record links to 3 conditions, with HIV appearing as the primary indexed condition, and to 2 interventions - of which HIIT (intervention) is the first listed.
NCT04550676 reports a single indexed study location in Colorado, Washington.
Frequently Asked Questions
What is clinical trial NCT04550676 about?
NCT04550676 is a clinical study titled "High-Intensity Exercise to Attenuate Limitations and Train Habits in Older Adults With HIV". This is a multi-site, randomized, single-blind (researchers), active treatment concurrent control trial with individuals aged 50-80 living with HIV who experience fatigue and live a sedentary lifestyle. The overall goals of this proposal are to determine whether high-intensity interval training (HII...
What is the current status of trial NCT04550676?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 118 participants. The study started on 2021-04-02. Estimated completion is 2025-11-24.
What conditions does trial NCT04550676 study?
This clinical trial studies the following conditions: HIV, Fatigue, Mobility Limitation.
What interventions are being tested in trial NCT04550676?
The interventions under investigation include: HIIT (intervention) (BEHAVIORAL), CME (active control) (BEHAVIORAL).
Who is sponsoring clinical trial NCT04550676?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04550676 being conducted?
This trial has 2 study locations across Colorado, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04550676's enrollment target sits among peer trials
118 144th of 303 higher than 159 of 303 other HIV trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other HIV trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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