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ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Paralysis: early-phase trial registry

5 of 14 indexed Paralysis trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,230 of 28,707 conditions by registered trial count.

14 US clinical trials · 5 currently recruiting · #1,230 of 28,707 conditions by registered trial count

Paralysis: 14 US clinical trials tracked, 5 recruiting.

Paralysis is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is MetroHealth Medical Center, running 2 of these trials.

Enrollment posture brief

Registry condition paralysis

OPEN 5 | RECR 36% | LATE 1 | EARLY 3 | RANK #1230 | SPON 2

Nearest open-share peer: Attention (36% recruiting · 14 trials)

Paralysis (this)36%Acute Respiratory Failure35.7%Adherence, Medication35.7%Acromegaly28.6%Abscess7.1%
Open-enrollment share among volume-matched conditions near Paralysis

Paralysis lists 5 open slots (36% of 14 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Paralysis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Paralysis is recruiting below its size-band peers.

    5 of 14 indexed trials (35.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Paralysis trials is spread across many organizations.

    MetroHealth Medical Center accounts for 2 of 14 trials (14.3%). 13 distinct sponsors appear on at least one study for this condition label.

  3. Most Paralysis trials plan to enrol fewer than 100 people.

    Median target enrolment is 12 among the 14 trials that report a genuine target (sentinel values excluded). 14 of those (100%) plan for fewer than 100 participants.

  4. Paralysis research is mostly interventional.

    14 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 22Phase 41

Open and recent trials

14 total, page 1 of 1

RECRUITING Early Phase 1 64 participants

Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis

Northwell Health

NCT04755699

RECRUITING NA 36 participants

Nomad P-KAFO Study

Shirley Ryan AbilityLab

NCT05644522

RECRUITING NA 25 participants

Operant Conditioning of Spinal Reflexes Training System--Reflex Operant Down Conditioning

Medical University of South Carolina

NCT05094362

RECRUITING NA 10 participants

Evaluation of an Advanced Lower Extremity Neuroprostheses

Case Western Reserve University

NCT00623389

RECRUITING NA 10 participants

A Neuroprosthesis for Seated Posture and Balance

VA Office of Research and Development

NCT01474148

ACTIVE NOT RECRUITING Phase 2 40 participants

Autologous Adipose Derived Mesenchymal Stem Cells for Spinal Cord Injury Patients

Mayo Clinic

NCT04520373

ACTIVE NOT RECRUITING NA 6 participants

COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis

Synchron Medical

NCT05035823

COMPLETED Phase 4 60 participants

The Early Reversibility of Rocuronium After Different Doses of Neostigmine

National Institutes of Health Clinical Center (CC)

NCT00001520

COMPLETED Phase 2 34 participants

Motor Recovery in Recent Stroke Patients Treated With Amphetamine and Physical Therapy

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00001783

COMPLETED NA 12 participants

Stimulation With Wire Leads to Restore Cough

MetroHealth Medical Center

NCT01659541

COMPLETED NA 7 participants

Restoring Arm and Hand Function With Non-invasive Spinal Stimulation

NeuroEnabling Technologies

NCT01906424

COMPLETED NA 6 participants

Short-Term Transcutaneous or Epidural Spinal Stimulation for Enabling Motor Function in Humans With SCI

Kristin Zhao, PhD

NCT05095454

COMPLETED NA 5 participants

Impact of Custom Assistive and Adaptive Technology in Rehabilitation

Madonna Rehabilitation Hospital

NCT03567239

COMPLETED NA 5 participants

Functional Electrical Stimulation for Production of Artificial Cough

MetroHealth Medical Center

NCT00589199

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 2
Phase 4 1

Named interventions

Most-linked intervention names on Paralysis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Transcutaneous electrical spinal stimulation Device
1 trials
Percutaneous epidural electrical spinal stimulation Device
1 trials
neostigmine Drug
1 trials
Placement and use of the device Procedure
1 trials
Using adaptive device. Device
1 trials
Transcutaneous Electrical Spinal Cord Stimulation Device
1 trials
0-15 Water Drug
1 trials
Implantation of device Procedure
1 trials

US sites by state

Facility locations filed on Paralysis trials. A trial with sites in several states counts in each.

Ohio 4 trials
New York 2 trials
Minnesota 2 trials
Maryland 2 trials
South Carolina 1 trials
Pennsylvania 1 trials
Nebraska 1 trials
Illinois 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Paralysis page

14 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Paralysis condition card totals 14 registered trials; most-linked intervention Transcutaneous electrical spinal stimulation; top US site state Ohio. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.