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ClinicalTrials.gov 5 recruiting now official registry

Paralysis clinical trials

5 of 14 indexed Paralysis trials are currently recruiting.

14 US clinical trials · 5 currently recruiting

Paralysis is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is MetroHealth Medical Center, running 2 of these trials.

The research picture

Paralysis has 14 registered US clinical trials, 5 of them open to new participants right now, about 36% of the total.

5
recruiting participants now
36%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
2
top sponsor: MetroHealth Medical Center
Phase 11Phase 22Phase 41

Active & Recent Trials

14 total, page 1 of 1

RECRUITING Early Phase 1 64 participants

Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis

Northwell Health

NCT04755699

RECRUITING NA 36 participants

Nomad P-KAFO Study

Shirley Ryan AbilityLab

NCT05644522

RECRUITING NA 25 participants

Operant Conditioning of Spinal Reflexes Training System--Reflex Operant Down Conditioning

Medical University of South Carolina

NCT05094362

RECRUITING NA 10 participants

Evaluation of an Advanced Lower Extremity Neuroprostheses

Case Western Reserve University

NCT00623389

RECRUITING NA 10 participants

A Neuroprosthesis for Seated Posture and Balance

VA Office of Research and Development

NCT01474148

ACTIVE NOT RECRUITING Phase 2 40 participants

Autologous Adipose Derived Mesenchymal Stem Cells for Spinal Cord Injury Patients

Mayo Clinic

NCT04520373

ACTIVE NOT RECRUITING NA 6 participants

COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis

Synchron Medical

NCT05035823

COMPLETED Phase 4 60 participants

The Early Reversibility of Rocuronium After Different Doses of Neostigmine

National Institutes of Health Clinical Center (CC)

NCT00001520

COMPLETED Phase 2 34 participants

Motor Recovery in Recent Stroke Patients Treated With Amphetamine and Physical Therapy

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00001783

COMPLETED NA 12 participants

Stimulation With Wire Leads to Restore Cough

MetroHealth Medical Center

NCT01659541

COMPLETED NA 7 participants

Restoring Arm and Hand Function With Non-invasive Spinal Stimulation

NeuroEnabling Technologies

NCT01906424

COMPLETED NA 6 participants

Short-Term Transcutaneous or Epidural Spinal Stimulation for Enabling Motor Function in Humans With SCI

Kristin Zhao, PhD

NCT05095454

COMPLETED NA 5 participants

Impact of Custom Assistive and Adaptive Technology in Rehabilitation

Madonna Rehabilitation Hospital

NCT03567239

COMPLETED NA 5 participants

Functional Electrical Stimulation for Production of Artificial Cough

MetroHealth Medical Center

NCT00589199

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 2
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Paralysis Trial Landscape

14 indexed Paralysis studies · 5 recruiting (36%).

Phase mix: 1 late (III/IV) vs 3 early (I/II).

Top sponsor: MetroHealth Medical Center (2 trials), 9 others listed. 14 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Paralysis?

PlainTrial tracks 14 US clinical trials for Paralysis, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Paralysis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.