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Paralysis clinical trials
Every US clinical trial registered for Paralysis — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
14 US clinical trials · 5 currently recruiting
The research picture
Paralysis has 14 registered US clinical trials, 5 of them open to new participants right now — about 36% of the total.
- 5
- recruiting participants now
- 36%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 2
- top sponsor: MetroHealth Medical Center
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis
Northwell Health
NCT04755699
Nomad P-KAFO Study
Shirley Ryan AbilityLab
NCT05644522
Operant Conditioning of Spinal Reflexes Training System--Reflex Operant Down Conditioning
Medical University of South Carolina
NCT05094362
Evaluation of an Advanced Lower Extremity Neuroprostheses
Case Western Reserve University
NCT00623389
A Neuroprosthesis for Seated Posture and Balance
VA Office of Research and Development
NCT01474148
Autologous Adipose Derived Mesenchymal Stem Cells for Spinal Cord Injury Patients
Mayo Clinic
NCT04520373
COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis
Synchron Medical
NCT05035823
The Early Reversibility of Rocuronium After Different Doses of Neostigmine
National Institutes of Health Clinical Center (CC)
NCT00001520
Motor Recovery in Recent Stroke Patients Treated With Amphetamine and Physical Therapy
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00001783
Stimulation With Wire Leads to Restore Cough
MetroHealth Medical Center
NCT01659541
Restoring Arm and Hand Function With Non-invasive Spinal Stimulation
NeuroEnabling Technologies
NCT01906424
Short-Term Transcutaneous or Epidural Spinal Stimulation for Enabling Motor Function in Humans With SCI
Kristin Zhao, PhD
NCT05095454
Impact of Custom Assistive and Adaptive Technology in Rehabilitation
Madonna Rehabilitation Hospital
NCT03567239
Functional Electrical Stimulation for Production of Artificial Cough
MetroHealth Medical Center
NCT00589199
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 2 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Paralysis Trial Landscape
ClinicalTrials.gov lists 14 US studies indexed under Paralysis, and 5 of those are currently open to recruitment — roughly 36% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Paralysis shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 3 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Paralysis is led by MetroHealth Medical Center with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 14 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Paralysis?
PlainTrial tracks 14 US clinical trials for Paralysis, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Paralysis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.