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NCT04500899 · ClinicalTrials.gov registry record · Phase 1
Use of Phenylephrine for Assessment of Mitral Regurgitation Severity
A Phase 1 study of Mitral Regurgitation, sponsored by Montefiore Medical Center.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 35
- Enrollment target
- 1
- Study location
NCT04500899 is a Phase 1 study of Mitral Regurgitation that is actively recruiting participants, run by Montefiore Medical Center. The registered enrollment target is 35 participants, below the 1,023-participant average among 26 other Mitral Regurgitation trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04500899, a Phase 1 study of Mitral Regurgitation, is actively recruiting participants, sponsored by Montefiore Medical Center.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 35 participants
- Enrollment target
- 1
- Study location
Study Summary
The study proposes to develop a phenylephrine protocol to be used during transesophageal echocardiography, whereby intravenous phenylephrine would be used to increase afterload with the intent to mimic the awake hemodynamic profile and variation that occurs with normal physical activity. The expectation is to see changes in severity of Mitral Regurgitation (MR) grade with increasing afterload, which in turn can provide more accurate quantification of MR severity to assist in clinical decision making.
Conditions Studied
Interventions
- DRUG Mydfrin
Study Locations (1)
New York
- Montefiore Medical Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 35 participants |
| Start Date | 2020-12-01 |
| Est. Completion | 2026-06 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04500899
The ClinicalTrials.gov registry entry for NCT04500899 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 35 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,023-participant average among 26 other Mitral Regurgitation trials with a reported enrollment target (97% lower). The listed sponsor is Montefiore Medical Center, which has 345 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Mitral Regurgitation appearing as the primary indexed condition, and to 1 intervention - of which Mydfrin is the first listed.
NCT04500899 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.
Frequently Asked Questions
What is clinical trial NCT04500899 about?
NCT04500899 is a clinical study titled "Use of Phenylephrine for Assessment of Mitral Regurgitation Severity". The study proposes to develop a phenylephrine protocol to be used during transesophageal echocardiography, whereby intravenous phenylephrine would be used to increase afterload with the intent to mimic the awake hemodynamic profile and variation that occurs with normal physical activity. The expecta...
What is the current status of trial NCT04500899?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 35 participants. The study started on 2020-12-01. Estimated completion is 2026-06.
What conditions does trial NCT04500899 study?
This clinical trial studies the following conditions: Mitral Regurgitation.
What interventions are being tested in trial NCT04500899?
The interventions under investigation include: Mydfrin (DRUG).
Who is sponsoring clinical trial NCT04500899?
This trial is sponsored by Montefiore Medical Center, which has 345 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04500899 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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