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NCT04353284 · ClinicalTrials.gov registry record · Phase 2

Camostat Mesylate in COVID-19 Outpatients

A Phase 2 study of COVID-19, sponsored by Yale University.

Completed
Registry status
Phase 2
Development phase
70
Enrollment target
1
Study location

NCT04353284: Completed Phase 2 study of COVID-19, sponsored by Yale University.

NCT04353284 is a Phase 2 study of COVID-19 that has completed, run by Yale University. The registered enrollment target is 70 participants, below the 38,465-participant average among 298 other COVID-19 trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04353284, a Phase 2 study of COVID-19, has completed, sponsored by Yale University.

COMPLETED
Registry status
Phase 2
Development phase
70 participants
Enrollment target
1
Study location

Study Summary

The rationale of the present clinical trial is that an orally available drug given to outpatients that could reduce the viral burden in the upper respiratory tract could forestall complications of SARS-CoV-2 infection and reduce transmission from one infected individual to another.

Primary Outcome

To determine whether camostat mesylate reduces SARS-COV-2 viral load (N Gene) in early COVID-19 disease, change from day 0 to day 4 in respiratory (oropharyngeal swab RT-PCR) log10 viral load will be assessed.

Conditions Studied

Interventions

  • OTHER Placebo
  • DRUG Camostat Mesilate

Study Locations (1)

Connecticut

  • Yale University - New Haven

Trial Details

FieldValue
Enrollment Target 70 participants
Start Date 2020-06-09
Est. Completion 2021-04-22
Phase Phase 2
Yale University

1,492 total trials

What the finished NCT04353284 record still lists

NCT04353284 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 38,465-participant average among 298 other COVID-19 trials with a reported enrollment target (100% lower).

The record links to 1 condition, with COVID-19 appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT04353284 reports a single indexed study location in Connecticut.

Frequently Asked Questions

What is clinical trial NCT04353284 about?

NCT04353284 is a clinical study titled "Camostat Mesylate in COVID-19 Outpatients". The rationale of the present clinical trial is that an orally available drug given to outpatients that could reduce the viral burden in the upper respiratory tract could forestall complications of SARS-CoV-2 infection and reduce transmission from one infected individual to another.

What is the current status of trial NCT04353284?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 70 participants. The study started on 2020-06-09. Estimated completion is 2021-04-22.

What conditions does trial NCT04353284 study?

This clinical trial studies the following conditions: COVID-19.

What interventions are being tested in trial NCT04353284?

The interventions under investigation include: Placebo (OTHER), Camostat Mesilate (DRUG).

Who is sponsoring clinical trial NCT04353284?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04353284 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for COVID-19

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04353284's enrollment target sits among peer trials

70 228th of 298 higher than 69 of 298 other COVID-19 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other COVID-19 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04353284, the US trial registry maintained by the National Library of Medicine. NCT04353284 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.