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2026 data Public-data reference. official source

Lower Urinary Tract Symptoms

Open-data reference.

22 US clinical trials · 7 currently recruiting

Active & Recent Trials

RECRUITING 7,500 participants

BPH Global Registry

Société Internationale d'Urologie

NCT05543200

RECRUITING NA 120 participants

5-Alpha Reductase 2 as a Marker of Resistance to 5ARI Therapy

Beth Israel Deaconess Medical Center

NCT04288427

RECRUITING 80 participants

US Imaging for the Assessment of LUTS

University of Wisconsin, Madison

NCT06323109

RECRUITING NA 68 participants

PRescription Exercise for Older Men With Urinary Disease

University of California, San Francis

NCT06225479

RECRUITING Phase 2 50 participants

Testing MitoQ on Lower Urinary Tract Symptoms in Older Women With Metabolic Syndrome

Iman Al-Naggar, PhD

NCT06351683

RECRUITING NA 36 participants

Preoperative Pelvic Floor Physical Therapy to Minimize Stress Urinary Incontinence After Holmium Laser Enucleation of the Prostate

The Cleveland Clinic

NCT06179654

RECRUITING NA 30 participants

HoLEP Prior to Radiation Therapy for Patients With LUTS/Retention and Concurrent Prostate Cancer

University of Kansas Medical Center

NCT03802851

ACTIVE NOT RECRUITING 840 participants

LURN: Urinary Urgency Phenotyping Protocol

Arbor Research Collaborative for Health

NCT04557748

ACTIVE NOT RECRUITING NA 208 participants

INTIBIA Pivotal Study

Coloplast A/S

NCT05250908

ACTIVE NOT RECRUITING NA 125 participants

Use of Artificial Intelligence by Urogynecologic Patients

Hartford Hospital

NCT06481436

COMPLETED 3,400 participants

RISE FOR HEALTH Study

University of Minnesota

NCT05365971

COMPLETED 1,879 participants

Symptoms of Lower Urinary Tract Dysfunction Phenotyping Study

Arbor Research Collaborative for Health

NCT02485808

COMPLETED Phase 2 689 participants

An 8-week, Open-label, Uncontrolled Study of Tamsulosin 0.4mg in Men With Bothersome Urinary Symptoms

Boehringer Ingelheim

NCT01726270

COMPLETED Phase 2 222 participants

Solifenacin Succinate With Tamsulosin HCl in Males With Lower Urinary Tract Symptoms and Bladder Outlet Obstruction

Astellas Pharma

NCT00507455

COMPLETED Phase 2 204 participants

Combined Behavioral and Drug Treatment of Overactive Bladder in Men

University of Alabama at Birmingham

NCT01175382

COMPLETED Phase 2 96 participants

Impact of Probiotics on Urinary Symptoms in Spinal Cord Injury SCI and SB

Medstar Health Research Institute

NCT02748317

COMPLETED Phase 3 74 participants

An Efficacy Study to Evaluate Alfuzosin to Treat Men With Erectile Dysfunction and Mild Lower Urinary Tract Symptoms

Chesapeake Urology Research Associates

NCT00893113

COMPLETED 72 participants

GentleCath™ for Men Intermittent Catheter With FeelClean™ Technology

ConvaTec

NCT05470751

COMPLETED NA 30 participants

Urological Biofeedback Game Software

University of Wisconsin, Madison

NCT02758938

COMPLETED Phase 4 12 participants

Higher Neural Changes Following Anticholinergic, Beta 3 Agonist, or Placebo in Patients With Overactive Bladder

Baylor Research Institute

NCT03817931

COMPLETED 12 participants

Central Nervous System Changes Following OnabotulinumtoxinA Injection in the Bladder

The Methodist Hospital Research Institute

NCT03033355

COMPLETED Phase 1 12 participants

Phase 1 Study of the Litx™ BPH System in Patients With Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH)

Light Sciences Oncology

NCT00709488

Phase Distribution

PhaseTrial count
Early Phase 1 1
Phase 2 5
Phase 3 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Lower Urinary Tract Symptoms Trial Landscape

ClinicalTrials.gov lists 22 US studies indexed under Lower Urinary Tract Symptoms, and 7 of those are currently open to recruitment — roughly 32% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Lower Urinary Tract Symptoms shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 6 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Lower Urinary Tract Symptoms is led by Arbor Research Collaborative for Health with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 22 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Lower Urinary Tract Symptoms?

PlainTrial tracks 22 US clinical trials for Lower Urinary Tract Symptoms, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Lower Urinary Tract Symptoms?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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