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ClinicalTrials.gov 7 recruiting now early-phase tilt

Lower Urinary Tract Symptoms: early-phase trial registry

7 of 22 indexed Lower Urinary Tract Symptoms trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #756 of 28,707 conditions by registered trial count.

22 US clinical trials · 7 currently recruiting · #756 of 28,707 conditions by registered trial count

Lower Urinary Tract Symptoms: 22 US clinical trials tracked, 7 recruiting.

Lower Urinary Tract Symptoms is the subject of 22 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Arbor Research Collaborative for Health, running 2 of these trials.

Enrollment posture brief

Registry condition lower-urinary-tract-symptoms

OPEN 7 | RECR 32% | LATE 2 | EARLY 6 | RANK #756 | SPON 2

Nearest open-share peer: Childhood Obesity (32% recruiting · 44 trials)

Advanced Melanoma63.6%Lower Urinary Tract Symp (th…32%Acute Myeloid Leukemia Arisi18.2%Adenocarcinoma of the Prosta0%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Lower Urinary Tract Symptoms

Lower Urinary Tract Symptoms lists 7 open slots (32% of 22 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Lower Urinary Tract Symptoms on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Lower Urinary Tract Symptoms is recruiting below its size-band peers.

    7 of 22 indexed trials (31.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Lower Urinary Tract Symptoms trials is spread across many organizations.

    Arbor Research Collaborative for Health accounts for 2 of 22 trials (9.1%). 20 distinct sponsors appear on at least one study for this condition label.

  3. Typical Lower Urinary Tract Symptoms enrolment sits around 96 participants.

    Median target enrolment is 96 among the 22 trials that report a genuine target (sentinel values excluded). 12 of those (54.5%) plan for fewer than 100 participants.

  4. Lower Urinary Tract Symptoms splits between interventional and observational designs.

    15 interventional and 7 observational studies make up this index (68.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 25Phase 31Phase 41

Open and recent trials

22 total, page 1 of 1

RECRUITING 7,500 participants

BPH Global Registry

Société Internationale d'Urologie

NCT05543200

RECRUITING NA 120 participants

5-Alpha Reductase 2 as a Marker of Resistance to 5ARI Therapy

Beth Israel Deaconess Medical Center

NCT04288427

RECRUITING 80 participants

US Imaging for the Assessment of LUTS

University of Wisconsin, Madison

NCT06323109

RECRUITING NA 68 participants

PRescription Exercise for Older Men With Urinary Disease

University of California, San Francisco

NCT06225479

RECRUITING Phase 2 50 participants

Testing MitoQ on Lower Urinary Tract Symptoms in Older Women With Metabolic Syndrome

Iman Al-Naggar, PhD

NCT06351683

RECRUITING NA 36 participants

Preoperative Pelvic Floor Physical Therapy to Minimize Stress Urinary Incontinence After Holmium Laser Enucleation of the Prostate

The Cleveland Clinic

NCT06179654

RECRUITING NA 30 participants

HoLEP Prior to Radiation Therapy for Patients With LUTS/Retention and Concurrent Prostate Cancer

University of Kansas Medical Center

NCT03802851

ACTIVE NOT RECRUITING 840 participants

LURN: Urinary Urgency Phenotyping Protocol

Arbor Research Collaborative for Health

NCT04557748

ACTIVE NOT RECRUITING NA 208 participants

INTIBIA Pivotal Study

Coloplast A/S

NCT05250908

ACTIVE NOT RECRUITING NA 125 participants

Use of Artificial Intelligence by Urogynecologic Patients

Hartford Hospital

NCT06481436

COMPLETED 3,400 participants

RISE FOR HEALTH Study

University of Minnesota

NCT05365971

COMPLETED 1,879 participants

Symptoms of Lower Urinary Tract Dysfunction Phenotyping Study

Arbor Research Collaborative for Health

NCT02485808

COMPLETED Phase 2 689 participants

An 8-week, Open-label, Uncontrolled Study of Tamsulosin 0.4mg in Men With Bothersome Urinary Symptoms

Boehringer Ingelheim

NCT01726270

COMPLETED Phase 2 222 participants

Solifenacin Succinate With Tamsulosin HCl in Males With Lower Urinary Tract Symptoms and Bladder Outlet Obstruction

Astellas Pharma

NCT00507455

COMPLETED Phase 2 204 participants

Combined Behavioral and Drug Treatment of Overactive Bladder in Men

University of Alabama at Birmingham

NCT01175382

COMPLETED Phase 2 96 participants

Impact of Probiotics on Urinary Symptoms in Spinal Cord Injury SCI and SB

Medstar Health Research Institute

NCT02748317

COMPLETED Phase 3 74 participants

An Efficacy Study to Evaluate Alfuzosin to Treat Men With Erectile Dysfunction and Mild Lower Urinary Tract Symptoms

Chesapeake Urology Research Associates

NCT00893113

COMPLETED 72 participants

GentleCath™ for Men Intermittent Catheter With FeelClean™ Technology

ConvaTec

NCT05470751

COMPLETED NA 30 participants

Urological Biofeedback Game Software

University of Wisconsin, Madison

NCT02758938

COMPLETED Phase 4 12 participants

Higher Neural Changes Following Anticholinergic, Beta 3 Agonist, or Placebo in Patients With Overactive Bladder

Baylor Research Institute

NCT03817931

COMPLETED 12 participants

Central Nervous System Changes Following OnabotulinumtoxinA Injection in the Bladder

The Methodist Hospital Research Institute

NCT03033355

COMPLETED Phase 1 12 participants

Phase 1 Study of the Litx™ BPH System in Patients With Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH)

Light Sciences Oncology

NCT00709488

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 5
Phase 3 1
Phase 4 1

Named interventions

Most-linked intervention names on Lower Urinary Tract Symptoms records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Urologic biofeedback software Other
1 trials
Combined Behavioral + Drug Therapy Other
1 trials
Tolterodine + tamsulosin Drug
1 trials
Behavioral training Behavioral
1 trials
Transurethral illumination with light emitting diodes (Litx™ BPH Device) Device
1 trials
Placement of device in prostate urethra Procedure
1 trials
Talaporfin sodium Drug
1 trials
Auditory Sensitivity Test Other
1 trials

US sites by state

Facility locations filed on Lower Urinary Tract Symptoms trials. A trial with sites in several states counts in each.

Texas 7 trials
California 7 trials
North Carolina 4 trials
Missouri 4 trials
Michigan 4 trials
Connecticut 4 trials
Alabama 4 trials
Washington 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Lower Urinary Tract Symptoms page

22 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Lower Urinary Tract Symptoms condition card totals 22 registered trials; most-linked intervention Urologic biofeedback software; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.