Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04253691 · ClinicalTrials.gov registry record · NA
Sleep Intervention for Chronic Insomnia Using Virtual Reality Pilot Study
A NA study of Pain, Chronic and Insomnia Chronic, sponsored by University of Missouri-Columbia.
- Active
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT04253691: Active NA study of Pain, Chronic and Insomnia Chronic, sponsored by University of Missouri-Columbia.
NCT04253691 is a NA study of Pain, Chronic and Insomnia Chronic that is active but no longer recruiting, run by University of Missouri-Columbia. The registered enrollment target is 30 participants, below the 721-participant average among 48 other Pain, Chronic trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04253691, a NA study of Pain, Chronic and Insomnia Chronic, is active but no longer recruiting, sponsored by University of Missouri-Columbia.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
Sleep disturbances are common among chronic pain patients, with reports typically ranging from 50-70% of patients reporting sleep difficulties. It is well documented that, alongside a high comorbidity with chronic pain, chronic insomnia also has high comorbidity with, and is a risk factor for, developing an anxiety disorders. This clinical trial will examine the effects of virtual reality (VR) meditation environments on patients with pain- and insomnia-related anxiety. The purpose of this study is to examine the benefits of using VR meditation with patients with chronic pain and chronic sleep disturbance so that clinicians can more effectively treat core causes to symptoms and reduce counterproductive therapies. Research objectives include: 1. To examine the clinical and health characteristics, including sleep, pain, fatigue, cognitive abilities, and cardiovascular health in patients with chronic pain. 2. To examine changes in the primary clinical outcomes, including chronic pain, complaints of poor sleep, and fatigue. 3. To examine changes in the secondary clinical outcomes, including mood, daytime functioning, cognitive functioning, and cardiovascular health. 4. To examine the mechanistic variables, including arousal (heart rate variability, HRV) and CS (thermal response).
Primary Outcome
Daily electronic dairies will record pain intensity and unpleasantness, sleep (latency, wake after onset, efficiency, quality), fatigue, sleep and pain medication consumption
Conditions Studied
Interventions
- DEVICE Virtual Reality Mediated Relaxation
Study Locations (1)
Missouri
- University of Missouri - Columbia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2020-02-09 |
| Est. Completion | 2025-12-30 |
| Phase | NA |
What the registry record for NCT04253691 still lists
NCT04253691 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 721-participant average among 48 other Pain, Chronic trials with a reported enrollment target (96% lower).
The record links to 2 conditions, with Pain, Chronic appearing as the primary indexed condition, and to 1 intervention - of which Virtual Reality Mediated Relaxation is the first listed.
NCT04253691 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT04253691 about?
NCT04253691 is a clinical study titled "Sleep Intervention for Chronic Insomnia Using Virtual Reality Pilot Study". Sleep disturbances are common among chronic pain patients, with reports typically ranging from 50-70% of patients reporting sleep difficulties. It is well documented that, alongside a high comorbidity with chronic pain, chronic insomnia also has high comorbidity with, and is a risk factor for, devel...
What is the current status of trial NCT04253691?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2020-02-09. Estimated completion is 2025-12-30.
What conditions does trial NCT04253691 study?
This clinical trial studies the following conditions: Pain, Chronic, Insomnia Chronic.
What interventions are being tested in trial NCT04253691?
The interventions under investigation include: Virtual Reality Mediated Relaxation (DEVICE).
Who is sponsoring clinical trial NCT04253691?
This trial is sponsored by University of Missouri-Columbia, which has 291 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04253691 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pain, Chronic
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04253691's enrollment target sits among peer trials
30 40th of 48 higher than 6 of 48 other Pain, Chronic trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain, Chronic trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study
RECRUITING · NA
-
Pain and Weight Treatment: Development and Trial of PAW
RECRUITING · NA
-
VR and Cooled Genicular Nerve Radio Frequency Ablation for Chronic Knee Pain
RECRUITING · NA
-
The PROACTIVE Study for Black Elders
RECRUITING · NA
-
Pain and Opioid Management in Older Adults
RECRUITING · NA
-
Evaluate the Impact of Targeted Physical Activity on Clinically Debilitated Dialysis Patients.
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00977977 · 30 participants · Phase 2
Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy
- NCT01459107 · 30 participants · Phase 2
Human Upper Extremity Allotransplantation
- NCT01666080 · 30 participants · NA
Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)
- NCT01720836 · 30 participants · Phase 1
Study of the Immune Response of MUC1 (Mucin1) Peptide Vaccine for Non-small Cell Lung Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI