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NCT04205656 · ClinicalTrials.gov registry record · Phase 1
Prospective Evaluation of PRP and BMC Treatment to Accelerate Healing After ACL Reconstruction
A Phase 1 study of Osteoarthritis, Knee, sponsored by Steadman Philippon Research Institute.
- Active
- Registry status
- Phase 1
- Development phase
- 45
- Enrollment target
- 1
- Study location
NCT04205656: Active Phase 1 study of Osteoarthritis, Knee, sponsored by Steadman Philippon Research Institute.
NCT04205656 is a Phase 1 study of Osteoarthritis, Knee that is active but no longer recruiting, run by Steadman Philippon Research Institute. The registered enrollment target is 45 participants, below the 497-participant average among 112 other Osteoarthritis, Knee trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04205656, a Phase 1 study of Osteoarthritis, Knee, is active but no longer recruiting, sponsored by Steadman Philippon Research Institute.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 45 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a prospective, randomized, placebo-controlled trial to evaluate potential beneficial effects of leukocyte-poor platelet rich plasma and bone marrow concentrate on the healing and health of critical joint tissues in the knee following anterior cruciate ligament (ACL) reconstruction. Bone marrow contains stem cells which can change into cells of various different tissue types, while platelet rich plasma contains growth factors. This trial will compare the two procedures against placebo.
Conditions Studied
Interventions
- BIOLOGICAL Leukocyte-Poor Platelet Rich Plasma (LP-PRP)
- BIOLOGICAL Bone Marrow Concentrate (BMC)
- OTHER Control group (Placebo)
Study Locations (1)
Colorado
- 181 West Meadow Drive, Suite 1000 - Vail
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2020-01-02 |
| Est. Completion | 2024-09 |
| Phase | Phase 1 |
What the registry record for NCT04205656 still lists
NCT04205656 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 497-participant average among 112 other Osteoarthritis, Knee trials with a reported enrollment target (91% lower).
The record links to 1 condition, with Osteoarthritis, Knee appearing as the primary indexed condition, and to 3 interventions - of which Leukocyte-Poor Platelet Rich Plasma (LP-PRP) is the first listed.
NCT04205656 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT04205656 about?
NCT04205656 is a clinical study titled "Prospective Evaluation of PRP and BMC Treatment to Accelerate Healing After ACL Reconstruction". This is a prospective, randomized, placebo-controlled trial to evaluate potential beneficial effects of leukocyte-poor platelet rich plasma and bone marrow concentrate on the healing and health of critical joint tissues in the knee following anterior cruciate ligament (ACL) reconstruction. Bone marr...
What is the current status of trial NCT04205656?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 45 participants. The study started on 2020-01-02. Estimated completion is 2024-09.
What conditions does trial NCT04205656 study?
This clinical trial studies the following conditions: Osteoarthritis, Knee.
What interventions are being tested in trial NCT04205656?
The interventions under investigation include: Leukocyte-Poor Platelet Rich Plasma (LP-PRP) (BIOLOGICAL), Bone Marrow Concentrate (BMC) (BIOLOGICAL), Control group (Placebo) (OTHER).
Who is sponsoring clinical trial NCT04205656?
This trial is sponsored by Steadman Philippon Research Institute, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04205656 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoarthritis, Knee
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04205656's enrollment target sits among peer trials
45 91st of 112 higher than 22 of 112 other Osteoarthritis, Knee trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoarthritis, Knee trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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