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NCT07070882 · ClinicalTrials.gov registry record · Phase 1
Oral Steroid Taper After Total Knee Arthroplasty
A Phase 1 study of Osteoarthritis, Knee, sponsored by Columbia University.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 130
- Enrollment target
- 1
- Study location
NCT07070882: Recruiting Phase 1 study of Osteoarthritis, Knee, sponsored by Columbia University.
NCT07070882 is a Phase 1 study of Osteoarthritis, Knee that is actively recruiting participants, run by Columbia University. The registered enrollment target is 130 participants, below the 497-participant average among 112 other Osteoarthritis, Knee trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07070882, a Phase 1 study of Osteoarthritis, Knee, is actively recruiting participants, sponsored by Columbia University.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 130 participants
- Enrollment target
- 1
- Study location
Study Summary
This study aims to evaluate the effectiveness of an oral methylprednisolone taper in reducing postoperative pain, opioid consumption, and nausea following primary total knee arthroplasty (TKA).
Primary Outcome
Pain will be assessed using a 0-100 visual analog scale (VAS), where 0 represents no pain and 100 represents the worst imaginable pain. Pain will be assessed during knee flexion to 90 degrees and with ambulation, and daily scores will be averaged across post-operative days 1-6 (POD1-6) for each patient to derive the primary outcome.
Conditions Studied
Interventions
- DRUG Methylprednisolone
Study Locations (1)
New York
- Columbia University Medical Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 130 participants |
| Start Date | 2025-06-20 |
| Est. Completion | 2027-06-20 |
| Phase | Phase 1 |
What NCT07070882 shows while recruiting
NCT07070882 is an interventional study that assigns participants to a tested intervention. The registered 130 participants enrollment target is mid-sized for trials with a published cap, below the 497-participant average among 112 other Osteoarthritis, Knee trials with a reported enrollment target (74% lower).
The record links to 1 condition, with Osteoarthritis, Knee appearing as the primary indexed condition, and to 1 intervention - of which Methylprednisolone is the first listed.
NCT07070882 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT07070882 about?
NCT07070882 is a clinical study titled "Oral Steroid Taper After Total Knee Arthroplasty". This study aims to evaluate the effectiveness of an oral methylprednisolone taper in reducing postoperative pain, opioid consumption, and nausea following primary total knee arthroplasty (TKA).
What is the current status of trial NCT07070882?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 130 participants. The study started on 2025-06-20. Estimated completion is 2027-06-20.
What conditions does trial NCT07070882 study?
This clinical trial studies the following conditions: Osteoarthritis, Knee.
What interventions are being tested in trial NCT07070882?
The interventions under investigation include: Methylprednisolone (DRUG).
Who is sponsoring clinical trial NCT07070882?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07070882 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoarthritis, Knee
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07070882's enrollment target sits among peer trials
130 52nd of 112 higher than 61 of 112 other Osteoarthritis, Knee trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoarthritis, Knee trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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