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NCT04114981 · ClinicalTrials.gov registry record · Phase 3
Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease
A Phase 3 study of Metastatic Malignant Neoplasm in the Brain, sponsored by Alliance for Clinical Trials in Oncology.
- Active
- Registry status
- Phase 3
- Development phase
- 242
- Enrollment target
- 20
- Study locations
NCT04114981 is a Phase 3 study of Metastatic Malignant Neoplasm in the Brain that is active but no longer recruiting, run by Alliance for Clinical Trials in Oncology. The registered enrollment target is 242 participants, above the 82-participant average among 43 other Metastatic Malignant Neoplasm in the Brain trials with a reported enrollment target (195% higher). The trial reports 20 study locations across 9 states.
The verdict
NCT04114981, a Phase 3 study of Metastatic Malignant Neoplasm in the Brain, is active but no longer recruiting, sponsored by Alliance for Clinical Trials in Oncology.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 242 participants
- Enrollment target
- 20
- Study locations
Study Summary
This phase III trial studies how well single fraction stereotactic radiosurgery works compared with fractionated stereotactic radiosurgery in treating patients with cancer that has spread to the brain from other parts of the body and has been removed by surgery. Single fraction stereotactic radiosurgery is a specialized radiation therapy that delivers a single, high dose of radiation directly to the tumor and may cause less damage to normal tissue. Fractionated stereotactic radiosurgery delivers multiple, smaller doses of radiation therapy over time. This study may help doctors find out if fractionated stereotactic radiosurgery is better or worse than the usual approach with single fraction stereotactic radiosurgery.
Conditions Studied
Interventions
- OTHER Questionnaire Administration
- PROCEDURE Quality-of-Life Assessment
- RADIATION Single Fraction Stereotactic Radiosurgery
- RADIATION Fractionated Stereotactic Radiosurgery
Study Locations (20)
Arizona
- Banner MD Anderson Cancer Center - Gilbert
- Banner Thunderbird Medical Center - Glendale
- Banner-University Medical Center Phoenix - Phoenix
- Mayo Clinic Hospital in Arizona - Phoenix
- Mayo Clinic in Arizona - Scottsdale
- University of Arizona Cancer Center-North Campus - Tucson
California
- UC San Diego Moores Cancer Center - La Jolla
- Los Angeles County-USC Medical Center - Los Angeles
- USC / Norris Comprehensive Cancer Center - Los Angeles
- Epic Care Cyberknife Center - Walnut Creek
Arkansas
- Mercy Hospital Fort Smith - Fort Smith
- NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro - Jonesboro
Colorado
- University of Colorado Hospital - Aurora
- UCHealth Memorial Hospital Central - Colorado Springs
Delaware
- Helen F Graham Cancer Center - Newark
- Beebe Health Campus - Rehoboth Beach
Alabama
- University of Alabama at Birmingham Cancer Center - Birmingham
Alaska
- Anchorage Radiation Therapy Center - Anchorage
Connecticut
- Yale University - New Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 242 participants |
| Start Date | 2019-11-19 |
| Est. Completion | 2028-03 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04114981
The ClinicalTrials.gov registry entry for NCT04114981 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 242 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 82-participant average among 43 other Metastatic Malignant Neoplasm in the Brain trials with a reported enrollment target (195% higher). The listed sponsor is Alliance for Clinical Trials in Oncology, which has 446 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Metastatic Malignant Neoplasm in the Brain appearing as the primary indexed condition, and to 4 interventions - of which Questionnaire Administration is the first listed.
NCT04114981 reports 20 study locations spanning 9 distinct geographic areas - top geographies include Arizona, California, Arkansas.
Frequently Asked Questions
What is clinical trial NCT04114981 about?
NCT04114981 is a clinical study titled "Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease". This phase III trial studies how well single fraction stereotactic radiosurgery works compared with fractionated stereotactic radiosurgery in treating patients with cancer that has spread to the brain from other parts of the body and has been removed by surgery. Single fraction stereotactic radiosur...
What is the current status of trial NCT04114981?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 242 participants. The study started on 2019-11-19. Estimated completion is 2028-03.
What conditions does trial NCT04114981 study?
This clinical trial studies the following conditions: Metastatic Malignant Neoplasm in the Brain.
What interventions are being tested in trial NCT04114981?
The interventions under investigation include: Questionnaire Administration (OTHER), Quality-of-Life Assessment (PROCEDURE), Single Fraction Stereotactic Radiosurgery (RADIATION), Fractionated Stereotactic Radiosurgery (RADIATION).
Who is sponsoring clinical trial NCT04114981?
This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 446 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04114981 being conducted?
This trial has 20 study locations across Alabama, Alaska, Arizona, Arkansas, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
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