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NCT04113798 · ClinicalTrials.gov registry record · NA
Exercise and Therapeutic Learning Among Women With PTSD
A NA study of PTSD, sponsored by University of Wisconsin, Madison.
- Completed
- Registry status
- NA
- Development phase
- 35
- Enrollment target
- 1
- Study location
NCT04113798: Completed NA study of PTSD, sponsored by University of Wisconsin, Madison.
NCT04113798 is a NA study of PTSD that has completed, run by University of Wisconsin, Madison. The registered enrollment target is 35 participants, below the 302-participant average among 154 other PTSD trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04113798, a NA study of PTSD, has completed, sponsored by University of Wisconsin, Madison.
- COMPLETED
- Registry status
- NA
- Development phase
- 35 participants
- Enrollment target
- 1
- Study location
Study Summary
This study aims to test whether aerobic exercise performed after fear extinction learning improves the consolidation and subsequent recall of the learned safety memories (i.e., fear extinction memories) among adult women with PTSD related to interpersonal violence exposure, and whether this effect is mediated by the ability of exercise to increase acute levels of Brain-Derived Neurotrophic Factor (BDNF) and endocannabinoids (eCB). Participants can expect to be on study for up to 90 days, participating in 4 study stages: Day 1 of Assessments, Day 2 of Fear Learning, Day 3 of Fear Extinction (and activity), and Day 4 of Recall of Fear Extinction.
Primary Outcome
Aim 1 fear extinction analyses consists of a 2 (group: low-intensity exercise vs moderate-intensity exercise) x 2 (cue: conditioned fear and safety) x 2 (task phase context: learning context vs extinction context) mixed design focused on Day 4 fear responding (skin conductance responses). SCR data will be acquired on a BIOPAC MP150 Data Acquisition System (BIOPAC Systems, Inc.) with electrodes placed on participant's left hand. Participants will be instructed to select an intensity of a 7/10 on
Conditions Studied
Interventions
- BEHAVIORAL Moderate Intensity Exercise
- BEHAVIORAL Low Intensity Exercise
- OTHER Day 1 Assessments
- OTHER Day 2 Fear Learning
- OTHER Day 3 Fear Extinction
Study Locations (1)
Wisconsin
- University of Wisconsin - Madison
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 35 participants |
| Start Date | 2019-04-08 |
| Est. Completion | 2020-01-21 |
| Phase | NA |
What the finished NCT04113798 record still lists
NCT04113798 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 35 participants, a relatively small participant target, below the 302-participant average among 154 other PTSD trials with a reported enrollment target (88% lower).
The record links to 1 condition, with PTSD appearing as the primary indexed condition, and to 5 interventions - of which Moderate Intensity Exercise is the first listed.
NCT04113798 reports a single indexed study location in Wisconsin.
Frequently Asked Questions
What is clinical trial NCT04113798 about?
NCT04113798 is a clinical study titled "Exercise and Therapeutic Learning Among Women With PTSD". This study aims to test whether aerobic exercise performed after fear extinction learning improves the consolidation and subsequent recall of the learned safety memories (i.e., fear extinction memories) among adult women with PTSD related to interpersonal violence exposure, and whether this effect i...
What is the current status of trial NCT04113798?
This trial is currently completed. It is a NA study. The enrollment target is 35 participants. The study started on 2019-04-08. Estimated completion is 2020-01-21.
What conditions does trial NCT04113798 study?
This clinical trial studies the following conditions: PTSD.
What interventions are being tested in trial NCT04113798?
The interventions under investigation include: Moderate Intensity Exercise (BEHAVIORAL), Low Intensity Exercise (BEHAVIORAL), Day 1 Assessments (OTHER), Day 2 Fear Learning (OTHER), Day 3 Fear Extinction (OTHER).
Who is sponsoring clinical trial NCT04113798?
This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04113798 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04113798's enrollment target sits among peer trials
35 117th of 154 higher than 37 of 154 other PTSD trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other PTSD trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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