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NCT04055376 · ClinicalTrials.gov registry record · NA
Daily Light and Sound Stimulation to Improve Brain Functions in Alzheimer's Disease
A NA study of Alzheimer Disease and Alzheimer Dementia, sponsored by Massachusetts Institute of Technology.
- Active
- Registry status
- NA
- Development phase
- 15
- Enrollment target
- 1
- Study location
NCT04055376: Active NA study of Alzheimer Disease and Alzheimer Dementia, sponsored by Massachusetts Institute of Technology.
NCT04055376 is a NA study of Alzheimer Disease and Alzheimer Dementia that is active but no longer recruiting, run by Massachusetts Institute of Technology. The registered enrollment target is 15 participants, below the 2,751-participant average among 306 other Alzheimer Disease trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04055376, a NA study of Alzheimer Disease and Alzheimer Dementia, is active but no longer recruiting, sponsored by Massachusetts Institute of Technology.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
- 1
- Study location
Study Summary
In this trial, the safety and effect of daily exposure to light and sound stimulation on people with mild Alzheimer's Disease (AD) will be studied. COVID-19 Amendment: Due to the ongoing suspension of all in-person humans subject research across MIT in response to the COVID-19 pandemic, all enrolled participants who have not completed their 6-month visit will have their visit postponed to 9 months with a follow up at 18 months. Subjects who have completed their 6-month visit will still be instructed to continue and return at Month 12 for an evaluation. OPTIONAL: If the subject would like to come in for an evaluation between Month 9 and 18, we will invite participants to come on Month 12 to complete cognitive testing and EEG.
Primary Outcome
Feasibility of daily at-home light and sound stimulation will be assessed by keeping track of the amount of time the GENUS device is used per day. The device will automatically log the start and end times of the device usage. The log data will be collected and assessed at the interim analysis time points (Month 1, Month 3) and later time points (Month 6 or 9 and Month 12 or 18).
Conditions Studied
Interventions
- DEVICE GENUS device (Active Settings)
- DEVICE GENUS device (Sham Settings)
Study Locations (1)
Massachusetts
- Massachusetts Institute of Technology - Cambridge
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2019-08-14 |
| Est. Completion | 2025-04-30 |
| Phase | NA |
What the registry record for NCT04055376 still lists
NCT04055376 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 2,751-participant average among 306 other Alzheimer Disease trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Alzheimer Disease appearing as the primary indexed condition, and to 2 interventions - of which GENUS device (Active Settings) is the first listed.
NCT04055376 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04055376 about?
NCT04055376 is a clinical study titled "Daily Light and Sound Stimulation to Improve Brain Functions in Alzheimer's Disease". In this trial, the safety and effect of daily exposure to light and sound stimulation on people with mild Alzheimer's Disease (AD) will be studied. COVID-19 Amendment: Due to the ongoing suspension of all in-person humans subject research across MIT in response to the COVID-19 pandemic, all enrolle...
What is the current status of trial NCT04055376?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 15 participants. The study started on 2019-08-14. Estimated completion is 2025-04-30.
What conditions does trial NCT04055376 study?
This clinical trial studies the following conditions: Alzheimer Disease, Alzheimer Dementia.
What interventions are being tested in trial NCT04055376?
The interventions under investigation include: GENUS device (Active Settings) (DEVICE), GENUS device (Sham Settings) (DEVICE).
Who is sponsoring clinical trial NCT04055376?
This trial is sponsored by Massachusetts Institute of Technology, which has 24 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04055376 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alzheimer Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04055376's enrollment target sits among peer trials
15 279th of 306 higher than 24 of 306 other Alzheimer Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alzheimer Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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