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NCT03981861 · ClinicalTrials.gov registry record · Phase 2
Metabolic and Neuro-Endocrine Effect of Treating PCOS in Adolescents
A Phase 2 study of PCOS, sponsored by Children's Mercy Hospital Kansas City.
- Completed
- Registry status
- Phase 2
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT03981861: Completed Phase 2 study of PCOS, sponsored by Children's Mercy Hospital Kansas City.
NCT03981861 is a Phase 2 study of PCOS that has completed, run by Children's Mercy Hospital Kansas City. The registered enrollment target is 12 participants, below the 82-participant average among 8 other PCOS trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03981861, a Phase 2 study of PCOS, has completed, sponsored by Children's Mercy Hospital Kansas City.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
To exam in the effect of a combination of low dose Metformin and Spironolactone on functional brain MRI, menstrual regulation and metabolism in adolescents with PCOS.
Primary Outcome
Measurement of glucose and insulin at baseline and 2 hours after 75g of glucola.
Conditions Studied
Interventions
- DRUG Metformin and Spironolactone
Study Locations (1)
Missouri
- Children's Mercy Hospital - Kansas City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2016-07-02 |
| Est. Completion | 2019-06-05 |
| Phase | Phase 2 |
What the finished NCT03981861 record still lists
NCT03981861 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 82-participant average among 8 other PCOS trials with a reported enrollment target (85% lower).
The record links to 1 condition, with PCOS appearing as the primary indexed condition, and to 1 intervention - of which Metformin and Spironolactone is the first listed.
NCT03981861 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT03981861 about?
NCT03981861 is a clinical study titled "Metabolic and Neuro-Endocrine Effect of Treating PCOS in Adolescents". To exam in the effect of a combination of low dose Metformin and Spironolactone on functional brain MRI, menstrual regulation and metabolism in adolescents with PCOS.
What is the current status of trial NCT03981861?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 12 participants. The study started on 2016-07-02. Estimated completion is 2019-06-05.
What conditions does trial NCT03981861 study?
This clinical trial studies the following conditions: PCOS.
What interventions are being tested in trial NCT03981861?
The interventions under investigation include: Metformin and Spironolactone (DRUG).
Who is sponsoring clinical trial NCT03981861?
This trial is sponsored by Children's Mercy Hospital Kansas City, which has 184 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03981861 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for PCOS
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03981861's enrollment target sits among peer trials
12 9th of 8 the lowest of 8 other PCOS trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other PCOS trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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