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NCT04034706 · ClinicalTrials.gov registry record
Transcriptional and Epigenetic Program of PCOS Women
A clinical trial of PCOS, sponsored by AdventHealth Translational Research Institute.
- Active
- Registry status
- 108
- Enrollment target
- 1
- Study location
NCT04034706: Active study of PCOS, sponsored by AdventHealth Translational Research Institute.
NCT04034706 is a study of PCOS that is active but no longer recruiting, run by AdventHealth Translational Research Institute. The registered enrollment target is 108 participants, above the 70-participant average among 8 other PCOS trials with a reported enrollment target (54% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04034706, a study of PCOS, is active but no longer recruiting, sponsored by AdventHealth Translational Research Institute.
- ACTIVE NOT RECRUITING
- Registry status
- 108 participants
- Enrollment target
- 1
- Study location
Study Summary
The main goal is to reveal differences in global gene expression in two different adipose tissue (AT) depots of females with and without polycystic ovary syndrome (PCOS) and how these are influenced by upstream epigenetic markers
Primary Outcome
Epigenetic profiles (DNA methylation) and gene expression (RNA-seq) will be performed on whole tissue abdominal fat and gluteofemoral fat biopsies in addition to cultured pre-adipocytes and adipocytes.
Conditions Studied
Interventions
- OTHER DEXA
- OTHER Magnetic Resonance (MR) Assessment of the Abdomen
- OTHER MR assessment of Whole Body Fat
- PROCEDURE Adipose tissue biopsy
- OTHER Oral glucose tolerance test
Study Locations (1)
Florida
- AdventHealth Translational Research Institute - Orlando
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 108 participants |
| Start Date | 2020-01-31 |
| Est. Completion | 2025-12 |
What the registry record for NCT04034706 still lists
NCT04034706 is an observational study that tracks outcomes without assigning an intervention. The registered 108 participants enrollment target is mid-sized for trials with a published cap, above the 70-participant average among 8 other PCOS trials with a reported enrollment target (54% higher).
The record links to 1 condition, with PCOS appearing as the primary indexed condition, and to 5 interventions - of which DEXA is the first listed.
NCT04034706 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT04034706 about?
NCT04034706 is a clinical study titled "Transcriptional and Epigenetic Program of PCOS Women". The main goal is to reveal differences in global gene expression in two different adipose tissue (AT) depots of females with and without polycystic ovary syndrome (PCOS) and how these are influenced by upstream epigenetic markers
What is the current status of trial NCT04034706?
This trial is currently active not recruiting. The enrollment target is 108 participants. The study started on 2020-01-31. Estimated completion is 2025-12.
What conditions does trial NCT04034706 study?
This clinical trial studies the following conditions: PCOS.
What interventions are being tested in trial NCT04034706?
The interventions under investigation include: DEXA (OTHER), Magnetic Resonance (MR) Assessment of the Abdomen (OTHER), MR assessment of Whole Body Fat (OTHER), Adipose tissue biopsy (PROCEDURE), Oral glucose tolerance test (OTHER).
Who is sponsoring clinical trial NCT04034706?
This trial is sponsored by AdventHealth Translational Research Institute, which has 54 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04034706 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for PCOS
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04034706's enrollment target sits among peer trials
108 3rd of 8 higher than 6 of 8 other PCOS trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other PCOS trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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