Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03929146 · ClinicalTrials.gov registry record · Phase 4

Liposomal Bupivacaine Versus Interscalene Nerve Block

A Phase 4 study of Pain, Postoperative, sponsored by University of Cincinnati.

Completed
Registry status
Phase 4
Development phase
76
Enrollment target
1
Study location

NCT03929146 is a Phase 4 study of Pain, Postoperative that has completed, run by University of Cincinnati. The registered enrollment target is 76 participants, below the 272-participant average among 108 other Pain, Postoperative trials with a reported enrollment target (72% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03929146, a Phase 4 study of Pain, Postoperative, has completed, sponsored by University of Cincinnati.

COMPLETED
Registry status
Phase 4
Development phase
76 participants
Enrollment target
1
Study location

Study Summary

The aim of this study is to compare two different pain management interventions in patients undergoing reverse total shoulder arthroplasty. The two interventions are 1) pre-operative interscalene nerve block and 2) intraoperative injection of liposomal bupivacaine (Exparel, Pacira Pharmaceuticals, Parsippany NJ). Specifically, the primary aims of this study are to compare these two interventions on the following: post-operative opioid consumption, pain scores, and patient satisfaction. Additionally, the investigators want to determine if psychological factors, catastrophizing and resilience, are associated with post-operative pain control and satisfaction. The investigators' hypothesis is that the two interventions will have similar pain control efficacy and that the liposomal bupivacaine group will experience faster post-operative recovery, earlier discharge, and improved satisfaction. The investigators also expect patient catastrophizing and resilience to significantly predict the degree of post-operative pain and level of patient satisfaction.

Conditions Studied

Interventions

  • DRUG Exparel
  • PROCEDURE Interscalene Nerve Block

Study Locations (1)

Ohio

  • University of Cincinnati Medical Center - Cincinnati

Trial Details

FieldValue
Enrollment Target 76 participants
Start Date 2019-02-05
Est. Completion 2022-11-01
Phase Phase 4

Sponsor

University of Cincinnati

245 total trials

What the Registry Record Tells You About NCT03929146

The ClinicalTrials.gov registry entry for NCT03929146 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 76 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 272-participant average among 108 other Pain, Postoperative trials with a reported enrollment target (72% lower). The listed sponsor is University of Cincinnati, which has 245 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Pain, Postoperative appearing as the primary indexed condition, and to 2 interventions - of which Exparel is the first listed.

NCT03929146 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT03929146 about?

NCT03929146 is a clinical study titled "Liposomal Bupivacaine Versus Interscalene Nerve Block". The aim of this study is to compare two different pain management interventions in patients undergoing reverse total shoulder arthroplasty. The two interventions are 1) pre-operative interscalene nerve block and 2) intraoperative injection of liposomal bupivacaine (Exparel, Pacira Pharmaceuticals, P...

What is the current status of trial NCT03929146?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 76 participants. The study started on 2019-02-05. Estimated completion is 2022-11-01.

What conditions does trial NCT03929146 study?

This clinical trial studies the following conditions: Pain, Postoperative.

What interventions are being tested in trial NCT03929146?

The interventions under investigation include: Exparel (DRUG), Interscalene Nerve Block (PROCEDURE).

Who is sponsoring clinical trial NCT03929146?

This trial is sponsored by University of Cincinnati, which has 245 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03929146 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Pain, Postoperative

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.