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NCT06757075 · ClinicalTrials.gov registry record · Phase 4
Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia
A Phase 4 study of Pain, Postoperative, sponsored by Boston University.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 75
- Enrollment target
- 1
- Study location
NCT06757075: Recruiting Phase 4 study of Pain, Postoperative, sponsored by Boston University.
NCT06757075 is a Phase 4 study of Pain, Postoperative that is actively recruiting participants, run by Boston University. The registered enrollment target is 75 participants, below the 272-participant average among 113 other Pain, Postoperative trials with a reported enrollment target (72% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06757075, a Phase 4 study of Pain, Postoperative, is actively recruiting participants, sponsored by Boston University.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to investigate the effectiveness of various oral analgesic regimens in minimizing post-operative pain and discomfort in young children following dental rehabilitation under general anesthesia (DRGA). In this randomized controlled trial, three analgesic regimens following DRGA in Franciscan Children's Hospital will be compared using both self-report and behavioral measures. The analgesic therapies to be investigated are ibuprofen monotherapy, alternating ibuprofen and acetaminophen dual-therapy, and combined ibuprofen and acetaminophen dual-therapy. For the purposes of this study, combined therapy is defined as the simultaneous administration of acetaminophen and ibuprofen at regular intervals, whereas alternating therapy is defined as one analgesic (acetaminophen or ibuprofen) administered within a 3 hour interval of the other.
Primary Outcome
The Dental Discomfort Questionnaire (DDQ-8)-Abbreviated is an 8 item questionnaire completed by the caregiver. Responses to each question are Yes=2 and No=0 creating a possible range of total scores of 0-16 with higher scores correlated with more dental discomfort.
Conditions Studied
Interventions
- DRUG Ibuprofen
- DRUG Acetominophen
Study Locations (1)
Massachusetts
- Franciscan Children's Hospital - Brighton
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2025-04-16 |
| Est. Completion | 2026-03 |
| Phase | Phase 4 |
What NCT06757075 shows while recruiting
NCT06757075 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 272-participant average among 113 other Pain, Postoperative trials with a reported enrollment target (72% lower).
The record links to 1 condition, with Pain, Postoperative appearing as the primary indexed condition, and to 2 interventions - of which Ibuprofen is the first listed.
NCT06757075 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06757075 about?
NCT06757075 is a clinical study titled "Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia". The purpose of this study is to investigate the effectiveness of various oral analgesic regimens in minimizing post-operative pain and discomfort in young children following dental rehabilitation under general anesthesia (DRGA). In this randomized controlled trial, three analgesic regimens following...
What is the current status of trial NCT06757075?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 75 participants. The study started on 2025-04-16. Estimated completion is 2026-03.
What conditions does trial NCT06757075 study?
This clinical trial studies the following conditions: Pain, Postoperative.
What interventions are being tested in trial NCT06757075?
The interventions under investigation include: Ibuprofen (DRUG), Acetominophen (DRUG).
Who is sponsoring clinical trial NCT06757075?
This trial is sponsored by Boston University, which has 185 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06757075 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pain, Postoperative
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06757075's enrollment target sits among peer trials
75 66th of 113 higher than 46 of 113 other Pain, Postoperative trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain, Postoperative trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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