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NCT06951867 · ClinicalTrials.gov registry record
Tezspire Cardiac Events PASS
A clinical trial of Cardiovascular Events and MACE, sponsored by AstraZeneca.
- Recruiting
- Registry status
- 16,640
- Enrollment target
- 4
- Study locations
NCT06951867: Recruiting study of Cardiovascular Events and MACE, sponsored by AstraZeneca.
NCT06951867 is a study of Cardiovascular Events and MACE that is actively recruiting participants, run by AstraZeneca. The registered enrollment target is 16,640 participants. The trial reports 4 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06951867, a study of Cardiovascular Events and MACE, is actively recruiting participants, sponsored by AstraZeneca.
- RECRUITING
- Registry status
- 16,640 participants
- Enrollment target
- 4
- Study locations
Study Summary
The aim of this study is to evaluate the risk of serious adverse cardiovascular events in adolescent and adult patients with severe asthma taking tezepelumab compared to a population receiving standard of care treatment for severe asthma.
Primary Outcome
The primary outcome of interest is the composite outcome MACE, consisting of non-fatal myocardial infarction, non-fatal stroke, or cardiovascular death.
Conditions Studied
Interventions
- DRUG Tezepelumab
Study Locations (4)
Other
- Danish registries (access/analysis) - Copenhagen
- French National Health Data System (SNDS) - Paris
- Team Gesundheit GKV Claims data (SHI) - Berlin
Delaware
- Healthcare Integrated Research Database (HIRD) - Wilmington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16,640 participants |
| Start Date | 2025-09-15 |
| Est. Completion | 2029-05-31 |
What NCT06951867 shows while recruiting
NCT06951867 is an observational study that tracks outcomes without assigning an intervention. Its 16,640 participants enrollment target places it among the larger protocols in the corpus.
The record links to 2 conditions, with Cardiovascular Events appearing as the primary indexed condition, and to 1 intervention - of which Tezepelumab is the first listed.
NCT06951867 reports a single indexed study location in Other, Delaware.
Frequently Asked Questions
What is clinical trial NCT06951867 about?
NCT06951867 is a clinical study titled "Tezspire Cardiac Events PASS". The aim of this study is to evaluate the risk of serious adverse cardiovascular events in adolescent and adult patients with severe asthma taking tezepelumab compared to a population receiving standard of care treatment for severe asthma.
What is the current status of trial NCT06951867?
This trial is currently recruiting. The enrollment target is 16,640 participants. The study started on 2025-09-15. Estimated completion is 2029-05-31.
What conditions does trial NCT06951867 study?
This clinical trial studies the following conditions: Cardiovascular Events, MACE.
What interventions are being tested in trial NCT06951867?
The interventions under investigation include: Tezepelumab (DRUG).
Who is sponsoring clinical trial NCT06951867?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06951867 being conducted?
This trial has 4 study locations across Delaware. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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