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NCT03845582 · ClinicalTrials.gov registry record · Phase 2
Phase 2/3 Study of ALK-001 in Geographic Atrophy
A Phase 2 study of Age-related Macular Degeneration and Geographic Atrophy, sponsored by Alkeus Pharmaceuticals.
- Completed
- Registry status
- Phase 2
- Development phase
- 200
- Enrollment target
- 20
- Study locations
NCT03845582: Completed Phase 2 study of Age-related Macular Degeneration and Geographic Atrophy, sponsored by Alkeus Pharmaceuticals.
NCT03845582 is a Phase 2 study of Age-related Macular Degeneration and Geographic Atrophy that has completed, run by Alkeus Pharmaceuticals. The registered enrollment target is 200 participants, below the 1,505-participant average among 74 other Age-related Macular Degeneration trials with a reported enrollment target (87% lower). The trial reports 20 study locations across 15 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03845582, a Phase 2 study of Age-related Macular Degeneration and Geographic Atrophy, has completed, sponsored by Alkeus Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 200 participants
- Enrollment target
- 20
- Study locations
Study Summary
This is a double-masked, multicenter, randomized, placebo-controlled clinical trial, evaluating the efficacy and safety of ALK-001 in participants with Geographic Atrophy (GA) secondary to age-related macular degeneration (AMD). Up to 200 participants will receive ALK-001 while up to 100 participants will receive a placebo.
Conditions Studied
Interventions
- DRUG Placebo oral capsule
- DRUG ALK-001 oral capsule
Study Locations (20)
Florida
- Alkeus Site - Clearwater
- Alkeus Site - Fort Myers
- Alkeus Site - Gainesville
- Alkeus Site - Tampa
- Alkeus Site - Winter Haven
New York
- Alkeus Site - Great Neck
- Alkeus Site - Hauppauge
Arizona
- Alkeus Site - Phoenix
California
- Alkeus Site - Beverly Hills
Colorado
- Alkeus Site - Lakewood
Illinois
- Alkeus Site - Bloomington
Kentucky
- Alkeus Site - Lexington
Maryland
- Alkeus Site - Chevy Chase
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2019-05-07 |
| Est. Completion | 2024-06-30 |
| Phase | Phase 2 |
What the finished NCT03845582 record still lists
NCT03845582 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, below the 1,505-participant average among 74 other Age-related Macular Degeneration trials with a reported enrollment target (87% lower).
The record links to 4 conditions, with Age-related Macular Degeneration appearing as the primary indexed condition, and to 2 interventions - of which Placebo oral capsule is the first listed.
NCT03845582 names 20 study sites across 15 states, led by Florida, New York, Arizona.
Frequently Asked Questions
What is clinical trial NCT03845582 about?
NCT03845582 is a clinical study titled "Phase 2/3 Study of ALK-001 in Geographic Atrophy". This is a double-masked, multicenter, randomized, placebo-controlled clinical trial, evaluating the efficacy and safety of ALK-001 in participants with Geographic Atrophy (GA) secondary to age-related macular degeneration (AMD). Up to 200 participants will receive ALK-001 while up to 100 participan...
What is the current status of trial NCT03845582?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 200 participants. The study started on 2019-05-07. Estimated completion is 2024-06-30.
What conditions does trial NCT03845582 study?
This clinical trial studies the following conditions: Age-related Macular Degeneration, Geographic Atrophy, AMD, Atrophy, Geographic.
What interventions are being tested in trial NCT03845582?
The interventions under investigation include: Placebo oral capsule (DRUG), ALK-001 oral capsule (DRUG).
Who is sponsoring clinical trial NCT03845582?
This trial is sponsored by Alkeus Pharmaceuticals, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03845582 being conducted?
This trial has 20 study locations across Arizona, California, Colorado, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03845582's enrollment target sits among peer trials
200 16th of 74 higher than 59 of 74 other Age-related Macular Degeneration trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Age-related Macular Degeneration trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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