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NCT03959163 · ClinicalTrials.gov registry record · NA

The Validity of the Quick Renal MRI in Pediatric Kidney Disease

A NA study of Pyelonephritis and Pyelonephritis Acute, sponsored by University of Wisconsin, Madison.

Recruiting
Registry status
NA
Development phase
100
Enrollment target
1
Study location

NCT03959163: Recruiting NA study of Pyelonephritis and Pyelonephritis Acute, sponsored by University of Wisconsin, Madison.

NCT03959163 is a NA study of Pyelonephritis and Pyelonephritis Acute that is actively recruiting participants, run by University of Wisconsin, Madison. The registered enrollment target is 100 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03959163, a NA study of Pyelonephritis and Pyelonephritis Acute, is actively recruiting participants, sponsored by University of Wisconsin, Madison.

RECRUITING
Registry status
NA
Development phase
100 participants
Enrollment target
1
Study location

Study Summary

The investigators propose a new imaging method for children born with congenital anomalies of the urinary tract that is a rapid, injection-, sedation-, and radiation-free alternative: the quick renal MRI. This proposal hypothesizes that the quick renal MRI has high validity compared to current radiologic standard for renal infection and scarring, the 99mTechnetium-dimercaptosuccinic acid (99mTc- DMSA) renal scan in the detection of acute renal infections and scars. If the quick renal MRI is accurate, it could potentially replace the DMSA scan for those specific questions and ease the burden of testing for children with chronic renal disease. Findings from these studies will provide preliminary data and rationale for a multi-centered study to further test this new technology. Participants will be 0-21 years of age and can expect to be on study for from 1 week (if enrolled in Aim 1) to 6 months (if enrolled in Aim 2).

Primary Outcome

Children admitted for suspected acute pyelonephritis will undergo a clinical DMSA (gold-standard) renal scan and quick renal MRI to determine the sensitivity of this method. The sensitivity will be calculated with True Positive (TP) / TP + False Negative (FN)

Interventions

  • DIAGNOSTIC_TEST Quick MRI

Study Locations (1)

Wisconsin

  • American Family Children's Hospital - Madison

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2019-05-07
Est. Completion 2025-01
Phase NA
University of Wisconsin, Madison

1,039 total trials

What NCT03959163 shows while recruiting

NCT03959163 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).

The record links to 3 conditions, with Pyelonephritis appearing as the primary indexed condition, and to 1 intervention - of which Quick MRI is the first listed.

NCT03959163 reports a single indexed study location in Wisconsin.

Frequently Asked Questions

What is clinical trial NCT03959163 about?

NCT03959163 is a clinical study titled "The Validity of the Quick Renal MRI in Pediatric Kidney Disease". The investigators propose a new imaging method for children born with congenital anomalies of the urinary tract that is a rapid, injection-, sedation-, and radiation-free alternative: the quick renal MRI. This proposal hypothesizes that the quick renal MRI has high validity compared to current radio...

What is the current status of trial NCT03959163?

This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2019-05-07. Estimated completion is 2025-01.

What conditions does trial NCT03959163 study?

This clinical trial studies the following conditions: Pyelonephritis, Pyelonephritis Acute, Renal Sclerosis.

What interventions are being tested in trial NCT03959163?

The interventions under investigation include: Quick MRI (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT03959163?

This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03959163 being conducted?

This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Pyelonephritis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03959163's enrollment target sits among peer trials

100 841st of 2000 higher than 1,081 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03959163, the US trial registry maintained by the National Library of Medicine. NCT03959163 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.