Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 2

A Study Evaluating the Safety and Clinical Activity of HCV-796 in Treatment-Naive and Non-Responder Subjects

NCT00367887 · View on ClinicalTrials.gov ↗

Study Summary

This is a phase 2, randomized, open-label study comparing the safety, antiviral activity, and pharmacokinetics of HCV-796 administered in combination with peginterferon alfa 2B (Peg-Intron) plus concomitant Rebetol vs. Peg-Intron plus Rebetol in Hepatitis C Virus (HCV) genotype 1-infected subjects who are either naive to treatment or who have previously failed treatment (non-responders).

Conditions Studied

Interventions

  • DRUG Peg-Intron
  • DRUG REBETOL
  • DRUG HCV 796

Study Locations (20)

California

  • Pfizer Investigational Site — Anaheim
  • Pfizer Investigational Site — La Jolla
  • Pfizer Investigational Site — La Jolla
  • Pfizer Investigational Site — Los Angeles
  • Pfizer Investigational Site — Pasadena
  • Pfizer Investigational Site — San Diego
  • Pfizer Investigational Site — San Diego
  • Pfizer Investigational Site — San Francisco
  • Pfizer Investigational Site — San Francisco

Florida

  • Pfizer Investigational Site — Gainesville
  • Pfizer Investigational Site — Miami

Massachusetts

  • Pfizer Investigational Site — Boston
  • Pfizer Investigational Site — Worcester

Minnesota

  • Pfizer Investigational Site — Plymouth
  • Pfizer Investigational Site — Saint Paul

District of Columbia

  • Pfizer Investigational Site — Washington D.C.

Georgia

  • Pfizer Investigational Site — Atlanta

Kentucky

  • Pfizer Investigational Site — Louisville

Michigan

  • Pfizer Investigational Site — Detroit

Trial Details

FieldValue
Enrollment Target 246 participants
Start Date 2006-10
Est. Completion 2008-07
Phase Phase 2

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00367887

The ClinicalTrials.gov registry entry for NCT00367887 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 246 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Wyeth is now a wholly owned subsidiary of Pfizer, which has 31 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Hepatitis C appearing as the primary indexed condition, and to 3 interventions — of which Peg-Intron is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00367887 reports 20 study locations spanning 9 distinct geographic areas — top geographies include California, Florida, Massachusetts. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00367887 about?

NCT00367887 is a clinical study titled "A Study Evaluating the Safety and Clinical Activity of HCV-796 in Treatment-Naive and Non-Responder Subjects". This is a phase 2, randomized, open-label study comparing the safety, antiviral activity, and pharmacokinetics of HCV-796 administered in combination with peginterferon alfa 2B (Peg-Intron) plus concomitant Rebetol vs. Peg-Intron plus Rebetol in Hepatitis C Virus (HCV) genotype 1-infected subjects ...

What is the current status of trial NCT00367887?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 246 participants. The study started on 2006-10. Estimated completion is 2008-07.

What conditions does trial NCT00367887 study?

This clinical trial studies the following conditions: Hepatitis C. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00367887?

The interventions under investigation include: Peg-Intron (DRUG), REBETOL (DRUG), HCV 796 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00367887?

This trial is sponsored by Wyeth is now a wholly owned subsidiary of Pfizer, which has 31 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00367887 being conducted?

This trial has 20 study locations across California, District of Columbia, Florida, Georgia, Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial