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NCT03705793 · ClinicalTrials.gov registry record · Phase 4

Effectiveness of Mometasone Nasal Irrigation for Chronic Rhinosinusitis

A Phase 4 study of Chronic Rhinosinusitis (Diagnosis) and Allergic Rhinosinusitis, sponsored by Washington University School of Medicine.

Completed
Registry status
Phase 4
Development phase
53
Enrollment target
2
Study locations

NCT03705793 is a Phase 4 study of Chronic Rhinosinusitis (Diagnosis) and Allergic Rhinosinusitis that has completed, run by Washington University School of Medicine. The registered enrollment target is 53 participants, below the 85-participant average among 9 other Chronic Rhinosinusitis (Diagnosis) trials with a reported enrollment target (38% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT03705793, a Phase 4 study of Chronic Rhinosinusitis (Diagnosis) and Allergic Rhinosinusitis, has completed, sponsored by Washington University School of Medicine.

COMPLETED
Registry status
Phase 4
Development phase
53 participants
Enrollment target
2
Study locations

Study Summary

Chronic rhinosinusitis (CRS) affects up to 12.5% of the US population and has a significant disease burden. The recommended medical management of CRS includes large-volume, low-pressure saline lavage, systemic antibiotics, and intranasal corticosteroids (INCS). While the efficacy and safety of INCS are well-established for the long-term management of CRS, penetration of INCS beyond the nasal vestibule and into the paranasal sinuses is limited. The aim of this study is to evaluate the effectiveness of mometasone furoate large-volume, low-pressure nasal irrigation for surgery-naive CRS patients.

Interventions

  • DRUG Mometasone Furoate Nasal Irrigation
  • DRUG Mometasone Nasal Spray

Study Locations (2)

Missouri

  • Washington University School of Medicine - St Louis
  • Washington University - St Louis

Trial Details

FieldValue
Enrollment Target 53 participants
Start Date 2019-01-01
Est. Completion 2020-03-15
Phase Phase 4

What the Registry Record Tells You About NCT03705793

The ClinicalTrials.gov registry entry for NCT03705793 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 53 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 85-participant average among 9 other Chronic Rhinosinusitis (Diagnosis) trials with a reported enrollment target (38% lower). The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Chronic Rhinosinusitis (Diagnosis) appearing as the primary indexed condition, and to 2 interventions - of which Mometasone Furoate Nasal Irrigation is the first listed.

NCT03705793 reports 2 study locations spanning 1 distinct geographic area - top geographies include Missouri.

Frequently Asked Questions

What is clinical trial NCT03705793 about?

NCT03705793 is a clinical study titled "Effectiveness of Mometasone Nasal Irrigation for Chronic Rhinosinusitis". Chronic rhinosinusitis (CRS) affects up to 12.5% of the US population and has a significant disease burden. The recommended medical management of CRS includes large-volume, low-pressure saline lavage, systemic antibiotics, and intranasal corticosteroids (INCS). While the efficacy and safety of INCS ...

What is the current status of trial NCT03705793?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 53 participants. The study started on 2019-01-01. Estimated completion is 2020-03-15.

What conditions does trial NCT03705793 study?

This clinical trial studies the following conditions: Chronic Rhinosinusitis (Diagnosis), Allergic Rhinosinusitis, Chronic Eosinophilic Rhinosinusitis.

What interventions are being tested in trial NCT03705793?

The interventions under investigation include: Mometasone Furoate Nasal Irrigation (DRUG), Mometasone Nasal Spray (DRUG).

Who is sponsoring clinical trial NCT03705793?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03705793 being conducted?

This trial has 2 study locations across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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