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NCT03388606 · ClinicalTrials.gov registry record

Characterization and Treatment of Adolescent Depression

A clinical trial of Depression, sponsored by National Institute of Mental Health (NIMH).

Recruiting
Registry status
4,100
Enrollment target
1
Study location

NCT03388606 is a study of Depression that is actively recruiting participants, run by National Institute of Mental Health (NIMH). The registered enrollment target is 4,100 participants, above the 780-participant average among 679 other Depression trials with a reported enrollment target (426% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT03388606, a study of Depression, is actively recruiting participants, sponsored by National Institute of Mental Health (NIMH).

RECRUITING
Registry status
4,100 participants
Enrollment target
1
Study location

Study Summary

This research study seeks to find causes and treatments of depression in teenagers. The study goals are to increase our knowledge of treatments for depression and understand how the brain changes when teenagers have depression. The study will also compare teenagers with depression to those without mental health diagnoses. This outpatient study is recruiting participants ages 11-17 who are depressed. They must have a pediatrician or other medical provider, be medically healthy, and able to perform research tasks. They may not currently be hospitalized, psychotic or actively suicidal. Teenagers with depression are eligible even if they are taking medication. The study begins with an evaluation that includes clinical assessment, interviews, and questionnaires. * Visits may include paper-and-pencil and computer tests of mood, memory, and thinking; specialized computer games; and structural and brain imaging. If eligible, study participants may return several times a year for up to two years. This part of the study does not involve treatment. * Participants may be eligible for outpatient treatment for up to 25 weeks. This includes evidenced-based "talk" therapy. Participants may choose either Interpersonal Psychotherapy for Adolescents (IPT-A) or Cognitive Behavioral Therapy (CBT). If indicated, participants may opt to receive standard medication treatments along with psychotherapy. Research includes computer tasks and brain imaging. All clinical evaluations, research tasks and visits are free of cost. Participants are compensated for research activities. Parents and teenager must agree to the teenager s participation in research. The study is conducted at the NIH in Bethesda, Maryland and enrolls participants from the Washington DC Metro region within 50 miles of NIH. Transportation expenses are reimbursed by NIMH.

Conditions Studied

Interventions

  • BEHAVIORAL Growth Mindset

Study Locations (1)

Maryland

  • National Institutes of Health Clinical Center - Bethesda

Trial Details

FieldValue
Enrollment Target 4,100 participants
Start Date 2017-12-28
Est. Completion 2026-07-01

What the Registry Record Tells You About NCT03388606

The ClinicalTrials.gov registry entry for NCT03388606 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 4,100 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 780-participant average among 679 other Depression trials with a reported enrollment target (426% higher). The listed sponsor is National Institute of Mental Health (NIMH), which has 343 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Depression appearing as the primary indexed condition, and to 1 intervention - of which Growth Mindset is the first listed.

NCT03388606 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT03388606 about?

NCT03388606 is a clinical study titled "Characterization and Treatment of Adolescent Depression". This research study seeks to find causes and treatments of depression in teenagers. The study goals are to increase our knowledge of treatments for depression and understand how the brain changes when teenagers have depression. The study will also compare teenagers with depression to those without m...

What is the current status of trial NCT03388606?

This trial is currently recruiting. The enrollment target is 4,100 participants. The study started on 2017-12-28. Estimated completion is 2026-07-01.

What conditions does trial NCT03388606 study?

This clinical trial studies the following conditions: Depression.

What interventions are being tested in trial NCT03388606?

The interventions under investigation include: Growth Mindset (BEHAVIORAL).

Who is sponsoring clinical trial NCT03388606?

This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03388606 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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