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NCT05969028 · ClinicalTrials.gov registry record · NA
First Responder Airway & Compression Rate Trial
A NA study of Out-Of-Hospital Cardiac Arrest, sponsored by University of Washington.
- Recruiting
- Registry status
- NA
- Development phase
- 4,200
- Enrollment target
- 1
- Study location
NCT05969028: Recruiting NA study of Out-Of-Hospital Cardiac Arrest, sponsored by University of Washington.
NCT05969028 is a NA study of Out-Of-Hospital Cardiac Arrest that is actively recruiting participants, run by University of Washington. The registered enrollment target is 4,200 participants, above the 593-participant average among 4 other Out-Of-Hospital Cardiac Arrest trials with a reported enrollment target (608% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05969028, a NA study of Out-Of-Hospital Cardiac Arrest, is actively recruiting participants, sponsored by University of Washington.
- RECRUITING
- Registry status
- NA
- Development phase
- 4,200 participants
- Enrollment target
- 1
- Study location
Study Summary
The First responder Airway \& Compression rate Trial (FACT) Study will address basic life support (BLS) treatments administered by Emergency Medical Services (EMS) first responders to patients who suffer a sudden circulatory (pulseless) collapse, referred to as sudden out-of-hospital cardiac arrest (SCA). The investigators propose a randomized controlled trial among persons who suffer SCA to compare these two rescue breathing approaches (standard Bag Valve Mask vs i-gel) along with evaluating a more precise chest compression rate within the range of 100-120 compressions per minute during CPR. Importantly, each of these treatments fall within established resuscitation guidelines and are already administered as part of standard care in clinical practice. Thus this proposed trial will essentially be comparing one standard-of-care treatment against another standard-of-care treatment. The study will address two primary aims: Aim 1: To compare survival to hospital discharge between SCA patients randomized to BVM versus the i-gel for rescue breathing. The hypothesis is that treatment with i-gel will result in a higher rate of survival to hospital discharge than BVM. Aim 2: To compare survival to hospital discharge between SCA patients randomized to chest compression rates of 100 versus 110 versus 120 per minute. The hypothesis is that treatment with 100 chest compressions per minute will result in a higher rate of survival to hospital discharge than compression rates of 110 or 120 per minute.
Primary Outcome
The outcome will compare the proportion of subjects who survive to be discharged from the hospital. The outcome is an endorsed outcome by the Utstein guidelines and a common primary outcome in clinical resuscitation studies.
Conditions Studied
Interventions
- DEVICE igel
- PROCEDURE Compression Rate
Study Locations (1)
Washington
- King County EMS - Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4,200 participants |
| Start Date | 2024-02-07 |
| Est. Completion | 2029-03 |
| Phase | NA |
What NCT05969028 shows while recruiting
NCT05969028 is an interventional study that assigns participants to a tested intervention. Its 4,200 participants enrollment target places it among the larger protocols in the corpus, above the 593-participant average among 4 other Out-Of-Hospital Cardiac Arrest trials with a reported enrollment target (608% higher).
The record links to 1 condition, with Out-Of-Hospital Cardiac Arrest appearing as the primary indexed condition, and to 2 interventions - of which igel is the first listed.
NCT05969028 reports a single indexed study location in Washington.
Frequently Asked Questions
What is clinical trial NCT05969028 about?
NCT05969028 is a clinical study titled "First Responder Airway & Compression Rate Trial". The First responder Airway \& Compression rate Trial (FACT) Study will address basic life support (BLS) treatments administered by Emergency Medical Services (EMS) first responders to patients who suffer a sudden circulatory (pulseless) collapse, referred to as sudden out-of-hospital cardiac arrest ...
What is the current status of trial NCT05969028?
This trial is currently recruiting. It is a NA study. The enrollment target is 4,200 participants. The study started on 2024-02-07. Estimated completion is 2029-03.
What conditions does trial NCT05969028 study?
This clinical trial studies the following conditions: Out-Of-Hospital Cardiac Arrest.
What interventions are being tested in trial NCT05969028?
The interventions under investigation include: igel (DEVICE), Compression Rate (PROCEDURE).
Who is sponsoring clinical trial NCT05969028?
This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05969028 being conducted?
This trial has 1 study location across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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