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NCT03365635 · ClinicalTrials.gov registry record · Phase 4

Administration of Zepatier (Grazoprevir Plus Elbasvir) in Chronic Hemodialysis (HD) Patients With Hepatitis C

A Phase 4 study of Hepatitis C and Hemodialysis, sponsored by University of Pennsylvania.

Completed
Registry status
Phase 4
Development phase
6
Enrollment target
1
Study location

NCT03365635: Completed Phase 4 study of Hepatitis C and Hemodialysis, sponsored by University of Pennsylvania.

NCT03365635 is a Phase 4 study of Hepatitis C and Hemodialysis that has completed, run by University of Pennsylvania. The registered enrollment target is 6 participants, below the 1,890-participant average among 106 other Hepatitis C trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03365635, a Phase 4 study of Hepatitis C and Hemodialysis, has completed, sponsored by University of Pennsylvania.

COMPLETED
Registry status
Phase 4
Development phase
6 participants
Enrollment target
1
Study location

Study Summary

This is a study to define strategies for Nephrologists to directly supervise and apply direct acting antivirals to cure hepatitis C in hemodialysis patients. Strategies will include identification of candidate patients, application for insurance approval, specifics of direct acting antiviral therapy (Zepatier with or without ribavirin) and laboratory monitoring during and after therapy.

Primary Outcome

Absence of HCV by viral RNA quantitation at 12 weeks post treatment

Interventions

  • DRUG Elbasvir 50 MG / Grazoprevir 100 MG [Zepatier]

Study Locations (1)

Pennsylvania

  • Penn Presbyterian Medical Center - Philadelphia

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2019-09-22
Est. Completion 2020-09-01
Phase Phase 4
University of Pennsylvania

1,423 total trials

What the finished NCT03365635 record still lists

NCT03365635 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 1,890-participant average among 106 other Hepatitis C trials with a reported enrollment target (100% lower).

The record links to 3 conditions, with Hepatitis C appearing as the primary indexed condition, and to 1 intervention - of which Elbasvir 50 MG / Grazoprevir 100 MG [Zepatier] is the first listed.

NCT03365635 reports a single indexed study location in Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT03365635 about?

NCT03365635 is a clinical study titled "Administration of Zepatier (Grazoprevir Plus Elbasvir) in Chronic Hemodialysis (HD) Patients With Hepatitis C". This is a study to define strategies for Nephrologists to directly supervise and apply direct acting antivirals to cure hepatitis C in hemodialysis patients. Strategies will include identification of candidate patients, application for insurance approval, specifics of direct acting antiviral therapy...

What is the current status of trial NCT03365635?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 6 participants. The study started on 2019-09-22. Estimated completion is 2020-09-01.

What conditions does trial NCT03365635 study?

This clinical trial studies the following conditions: Hepatitis C, Hemodialysis, Nosocomial Infection.

What interventions are being tested in trial NCT03365635?

The interventions under investigation include: Elbasvir 50 MG / Grazoprevir 100 MG [Zepatier] (DRUG).

Who is sponsoring clinical trial NCT03365635?

This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03365635 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Hepatitis C

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03365635's enrollment target sits among peer trials

6 105th of 106 higher than 2 of 106 other Hepatitis C trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Hepatitis C trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03365635, the US trial registry maintained by the National Library of Medicine. NCT03365635 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.