Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Hemodialysis clinical trials
Every US clinical trial registered for Hemodialysis — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
13 US clinical trials · 5 currently recruiting
The research picture
Hemodialysis has 13 registered US clinical trials, 5 of them open to new participants right now — about 38% of the total.
- 5
- recruiting participants now
- 38%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 1
- top sponsor: Cara Therapeutics
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
A Randomized Controlled Trial of Thyroid Hormone Supplementation in Hemodialysis Patients
University of California, Irvine
NCT03977207
A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease
W.L.Gore & Associates
NCT04671771
Angiotensin-Neprilysin Inhibition in Hemodialysis Initiation
Brigham and Women's Hospital
NCT05498181
Contactless Optical Monitoring of AV Access Using the PatenSee System in Outpatient Hemodialysis Patients
PatenSee
NCT07194395
Physical Activity Prescription Program for Hemodialysis Patients
University of Arizona
NCT06830993
Trial to Evaluate and Assess the Effect of Comprehensive Pre-ESKD Education on Home Dialysis Use in Veterans
VA Office of Research and Development
NCT04064086
Improving Blood Pressure Control in End-Stage Renal Disease Through a Supportive-Educative Nursing Intervention
Wayne State University
NCT01052220
Safety, Tolerability, and Feasibility of Empagliflozin Therapy in Dialysis-dependent ESKD
University of Utah
NCT05614115
Efficacy of Twice Weekly Hemodialysis in Patients With Residual Kidney Function
Palo Alto Veterans Institute for Research
NCT03874117
Comparison of Different Glucose Concentrations in Dialysate of Hemodialysis Patients
Renal Research Institute
NCT00618033
Measuring Cardiovascular Stress in Patients on Hemodialysis
West Penn Allegheny Health System
NCT01267617
Study to Evaluate the Pharmacokinetics and Metabolism of [14C] CR845 (Difelikefalin) in Patients With End Stage Renal Disease on Hemodialysis and in Healthy Subjects
Cara Therapeutics
NCT03947970
Administration of Zepatier (Grazoprevir Plus Elbasvir) in Chronic Hemodialysis (HD) Patients With Hepatitis C
University of Pennsylvania
NCT03365635
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 1 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Hemodialysis Trial Landscape
ClinicalTrials.gov lists 13 US studies indexed under Hemodialysis, and 5 of those are currently open to recruitment — roughly 38% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Hemodialysis shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 3 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Hemodialysis is led by Cara Therapeutics with 1 indexed trial, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 13 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Hemodialysis?
PlainTrial tracks 13 US clinical trials for Hemodialysis, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Hemodialysis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.