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ClinicalTrials.gov 5 recruiting now official registry

Hemodialysis clinical trials

5 of 13 indexed Hemodialysis trials are currently recruiting.

13 US clinical trials · 5 currently recruiting

Hemodialysis is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Cara Therapeutics, running 1 of these trials.

The research picture

Hemodialysis has 13 registered US clinical trials, 5 of them open to new participants right now, about 38% of the total.

5
recruiting participants now
38%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
1
top sponsor: Cara Therapeutics
Phase 12Phase 21Phase 41

Active & Recent Trials

13 total, page 1 of 1

RECRUITING NA 336 participants

A Randomized Controlled Trial of Thyroid Hormone Supplementation in Hemodialysis Patients

University of California, Irvine

NCT03977207

RECRUITING NA 133 participants

A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease

W.L.Gore & Associates

NCT04671771

RECRUITING Phase 2 100 participants

Angiotensin-Neprilysin Inhibition in Hemodialysis Initiation

Brigham and Women's Hospital

NCT05498181

RECRUITING 90 participants

Contactless Optical Monitoring of AV Access Using the PatenSee System in Outpatient Hemodialysis Patients

PatenSee

NCT07194395

RECRUITING NA 40 participants

Physical Activity Prescription Program for Hemodialysis Patients

University of Arizona

NCT06830993

ACTIVE NOT RECRUITING NA 656 participants

Trial to Evaluate and Assess the Effect of Comprehensive Pre-ESKD Education on Home Dialysis Use in Veterans

VA Office of Research and Development

NCT04064086

COMPLETED NA 118 participants

Improving Blood Pressure Control in End-Stage Renal Disease Through a Supportive-Educative Nursing Intervention

Wayne State University

NCT01052220

COMPLETED Phase 1 62 participants

Safety, Tolerability, and Feasibility of Empagliflozin Therapy in Dialysis-dependent ESKD

University of Utah

NCT05614115

COMPLETED NA 58 participants

Efficacy of Twice Weekly Hemodialysis in Patients With Residual Kidney Function

Palo Alto Veterans Institute for Research

NCT03874117

COMPLETED NA 30 participants

Comparison of Different Glucose Concentrations in Dialysate of Hemodialysis Patients

Renal Research Institute

NCT00618033

COMPLETED 26 participants

Measuring Cardiovascular Stress in Patients on Hemodialysis

West Penn Allegheny Health System

NCT01267617

COMPLETED Phase 1 12 participants

Study to Evaluate the Pharmacokinetics and Metabolism of [14C] CR845 (Difelikefalin) in Patients With End Stage Renal Disease on Hemodialysis and in Healthy Subjects

Cara Therapeutics

NCT03947970

COMPLETED Phase 4 6 participants

Administration of Zepatier (Grazoprevir Plus Elbasvir) in Chronic Hemodialysis (HD) Patients With Hepatitis C

University of Pennsylvania

NCT03365635

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Hemodialysis Trial Landscape

13 indexed Hemodialysis studies · 5 recruiting (38%).

Phase mix: 1 late (III/IV) vs 3 early (I/II).

Top sponsor: Cara Therapeutics (1 trial), 9 others listed. 13 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Hemodialysis?

PlainTrial tracks 13 US clinical trials for Hemodialysis, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Hemodialysis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.