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ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Hemodialysis: early-phase trial registry

5 of 13 indexed Hemodialysis trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,315 of 28,707 conditions by registered trial count.

13 US clinical trials · 5 currently recruiting · #1,315 of 28,707 conditions by registered trial count

Hemodialysis: 13 US clinical trials tracked, 5 recruiting.

Hemodialysis is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Cara Therapeutics, running 1 of these trials.

Enrollment posture brief

Registry condition hemodialysis

OPEN 5 | RECR 38% | LATE 1 | EARLY 3 | RANK #1315 | SPON 1

Nearest open-share peer: Anaplastic Oligodendroglioma (38% recruiting · 13 trials)

ACL Injury61.5%Acute Biphenotypic Leukemia46.2%Hemodialysis (this)38%Accidental Falls30.8%Actinic Keratoses23.1%
Open-enrollment share among volume-matched conditions near Hemodialysis

Hemodialysis lists 5 open slots (38% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Hemodialysis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Hemodialysis is recruiting below its size-band peers.

    5 of 13 indexed trials (38.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Hemodialysis trials is spread across many organizations.

    Cara Therapeutics accounts for 1 of 13 trials (7.7%). 13 distinct sponsors appear on at least one study for this condition label.

  3. Most Hemodialysis trials plan to enrol fewer than 100 people.

    Median target enrolment is 62 among the 13 trials that report a genuine target (sentinel values excluded). 8 of those (61.5%) plan for fewer than 100 participants.

  4. Hemodialysis research is mostly interventional.

    11 interventional and 2 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 21Phase 41

Open and recent trials

13 total, page 1 of 1

RECRUITING NA 336 participants

A Randomized Controlled Trial of Thyroid Hormone Supplementation in Hemodialysis Patients

University of California, Irvine

NCT03977207

RECRUITING NA 133 participants

A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease

W.L.Gore & Associates

NCT04671771

RECRUITING Phase 2 100 participants

Angiotensin-Neprilysin Inhibition in Hemodialysis Initiation

Brigham and Women's Hospital

NCT05498181

RECRUITING 90 participants

Contactless Optical Monitoring of AV Access Using the PatenSee System in Outpatient Hemodialysis Patients

PatenSee

NCT07194395

RECRUITING NA 40 participants

Physical Activity Prescription Program for Hemodialysis Patients

University of Arizona

NCT06830993

ACTIVE NOT RECRUITING NA 656 participants

Trial to Evaluate and Assess the Effect of Comprehensive Pre-ESKD Education on Home Dialysis Use in Veterans

VA Office of Research and Development

NCT04064086

COMPLETED NA 118 participants

Improving Blood Pressure Control in End-Stage Renal Disease Through a Supportive-Educative Nursing Intervention

Wayne State University

NCT01052220

COMPLETED Phase 1 62 participants

Safety, Tolerability, and Feasibility of Empagliflozin Therapy in Dialysis-dependent ESKD

University of Utah

NCT05614115

COMPLETED NA 58 participants

Efficacy of Twice Weekly Hemodialysis in Patients With Residual Kidney Function

Palo Alto Veterans Institute for Research

NCT03874117

COMPLETED NA 30 participants

Comparison of Different Glucose Concentrations in Dialysate of Hemodialysis Patients

Renal Research Institute

NCT00618033

COMPLETED 26 participants

Measuring Cardiovascular Stress in Patients on Hemodialysis

West Penn Allegheny Health System

NCT01267617

COMPLETED Phase 1 12 participants

Study to Evaluate the Pharmacokinetics and Metabolism of [14C] CR845 (Difelikefalin) in Patients With End Stage Renal Disease on Hemodialysis and in Healthy Subjects

Cara Therapeutics

NCT03947970

COMPLETED Phase 4 6 participants

Administration of Zepatier (Grazoprevir Plus Elbasvir) in Chronic Hemodialysis (HD) Patients With Hepatitis C

University of Pennsylvania

NCT03365635

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 1
Phase 4 1

Named interventions

Most-linked intervention names on Hemodialysis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

[14C] CR845 Drug
1 trials
Thrice Weekly Hemodialysis then Twice Weekly Hemodialysis Other
1 trials
Twice Weekly Hemodialysis then Thrice Weekly Hemodialysis Other
1 trials
Supportive Educative Nursing Intervention Behavioral
1 trials
BP education and BP self-regulation Behavioral
1 trials
Hemodialysis Procedure
1 trials
Elbasvir 50 MG / Grazoprevir 100 MG [Zepatier] Drug
1 trials
Provision of the freely available resources for Kidney Disease Education Other
1 trials

US sites by state

Facility locations filed on Hemodialysis trials. A trial with sites in several states counts in each.

Pennsylvania 3 trials
Texas 2 trials
New York 2 trials
Michigan 2 trials
Massachusetts 2 trials
Florida 2 trials
California 2 trials
Arizona 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Hemodialysis page

13 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Hemodialysis condition card totals 13 registered trials; most-linked intervention [14C] CR845; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.