Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03348384 · ClinicalTrials.gov registry record · Early Phase 1
[11C]NOP-1A and Cocaine Use Disorders
A Early Phase 1 study of Cocaine Use Disorder, sponsored by University of Pittsburgh.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 49
- Enrollment target
- 1
- Study location
NCT03348384: Completed Early Phase 1 study of Cocaine Use Disorder, sponsored by University of Pittsburgh.
NCT03348384 is a Early Phase 1 study of Cocaine Use Disorder that has completed, run by University of Pittsburgh. The registered enrollment target is 49 participants, below the 102-participant average among 26 other Cocaine Use Disorder trials with a reported enrollment target (52% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03348384, a Early Phase 1 study of Cocaine Use Disorder, has completed, sponsored by University of Pittsburgh.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 49 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to compared \[C-11\]NOP-1A binding in recently abstinent cocaine use disorders and controls.
Primary Outcome
VT-volume of distribution expressed relative to total plasma
Conditions Studied
Interventions
- RADIATION [C-11]
- DRUG NOP-1A
Study Locations (1)
Pennsylvania
- University of Pittsburgh - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 49 participants |
| Start Date | 2014-10-30 |
| Est. Completion | 2019-02-20 |
| Phase | Early Phase 1 |
What the finished NCT03348384 record still lists
NCT03348384 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 49 participants, a relatively small participant target, below the 102-participant average among 26 other Cocaine Use Disorder trials with a reported enrollment target (52% lower).
The record links to 1 condition, with Cocaine Use Disorder appearing as the primary indexed condition, and to 2 interventions - of which [C-11] is the first listed.
NCT03348384 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT03348384 about?
NCT03348384 is a clinical study titled "[11C]NOP-1A and Cocaine Use Disorders". The goal of this study is to compared \[C-11\]NOP-1A binding in recently abstinent cocaine use disorders and controls.
What is the current status of trial NCT03348384?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 49 participants. The study started on 2014-10-30. Estimated completion is 2019-02-20.
What conditions does trial NCT03348384 study?
This clinical trial studies the following conditions: Cocaine Use Disorder.
What interventions are being tested in trial NCT03348384?
The interventions under investigation include: [C-11] (RADIATION), NOP-1A (DRUG).
Who is sponsoring clinical trial NCT03348384?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03348384 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cocaine Use Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03348384's enrollment target sits among peer trials
49 15th of 26 higher than 12 of 26 other Cocaine Use Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cocaine Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Cocaine and Pentoxifylline (BED IN 47)
RECRUITING · Early Phase 1
-
Behavioral Effects of Drugs (Inpatient): 43 (Opioids, Cocaine, n-Acetylcysteine)
RECRUITING · Early Phase 1
-
Imaging CRF X NOP Interactions in CUD
RECRUITING · Early Phase 1
-
[C-11]NPA PET-amphetamine in Cocaine Use Disorders
RECRUITING · Early Phase 1
-
Safety Profile of Psilocybin for Cocaine Use Disorder
RECRUITING · Early Phase 1
-
Targeting Drug Memories With Methylphenidate
ACTIVE NOT RECRUITING · Early Phase 1
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02704858 · 49 participants · Phase 1
Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma
- NCT03516708 · 49 participants · Phase 1
Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer
- NCT03692429 · 49 participants · Phase 1
alloSHRINK - Standard cHemotherapy Regimen and Immunotherapy With Allogeneic NKG2D-based CYAD-101 Chimeric Antigen Receptor T-cells
- NCT04329494 · 49 participants · Phase 1
PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI