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NCT03341806 · ClinicalTrials.gov registry record · Phase 1

Avelumab With Laser Interstitial Therapy for Recurrent Glioblastoma

A Phase 1 study of Glioblastoma and GBM, sponsored by Icahn School of Medicine at Mount Sinai.

Completed
Registry status
Phase 1
Development phase
13
Enrollment target
1
Study location

NCT03341806 is a Phase 1 study of Glioblastoma and GBM that has completed, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 13 participants, below the 109-participant average among 199 other Glioblastoma trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03341806, a Phase 1 study of Glioblastoma and GBM, has completed, sponsored by Icahn School of Medicine at Mount Sinai.

COMPLETED
Registry status
Phase 1
Development phase
13 participants
Enrollment target
1
Study location

Study Summary

The purpose of the study is to characterize the safety and tolerability of avelumab in combination with Laser Interstitial Thermal Therapy (LITT) for blood barrier disruption in patients with recurrent glioblastoma.

Conditions Studied

Interventions

  • DRUG Avelumab
  • COMBINATION_PRODUCT MRI-guided LITT therapy

Study Locations (1)

New York

  • Icahn School of Medicine at Mount Sinai - New York

Trial Details

FieldValue
Enrollment Target 13 participants
Start Date 2018-06-13
Est. Completion 2021-10-13
Phase Phase 1

What the Registry Record Tells You About NCT03341806

The ClinicalTrials.gov registry entry for NCT03341806 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 13 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 109-participant average among 199 other Glioblastoma trials with a reported enrollment target (88% lower). The listed sponsor is Icahn School of Medicine at Mount Sinai, which has 708 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Glioblastoma appearing as the primary indexed condition, and to 2 interventions - of which Avelumab is the first listed.

NCT03341806 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT03341806 about?

NCT03341806 is a clinical study titled "Avelumab With Laser Interstitial Therapy for Recurrent Glioblastoma". The purpose of the study is to characterize the safety and tolerability of avelumab in combination with Laser Interstitial Thermal Therapy (LITT) for blood barrier disruption in patients with recurrent glioblastoma.

What is the current status of trial NCT03341806?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 13 participants. The study started on 2018-06-13. Estimated completion is 2021-10-13.

What conditions does trial NCT03341806 study?

This clinical trial studies the following conditions: Glioblastoma, GBM.

What interventions are being tested in trial NCT03341806?

The interventions under investigation include: Avelumab (DRUG), MRI-guided LITT therapy (COMBINATION_PRODUCT).

Who is sponsoring clinical trial NCT03341806?

This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03341806 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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