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NCT03311646 · ClinicalTrials.gov registry record · NA
Impact of Exclusive Use of Low Nicotine Cigarettes on Compensatory Smoking
A NA study of Smoking, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- NA
- Development phase
- 31
- Enrollment target
- 1
- Study location
NCT03311646: Completed NA study of Smoking, sponsored by Medical University of South Carolina.
NCT03311646 is a NA study of Smoking that has completed, run by Medical University of South Carolina. The registered enrollment target is 31 participants, below the 455-participant average among 123 other Smoking trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03311646, a NA study of Smoking, has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- NA
- Development phase
- 31 participants
- Enrollment target
- 1
- Study location
Study Summary
Smoking is the leading cause of preventable death in the United States. An FDA-mandated reduction in the nicotine content of cigarettes might reduce the health burden of tobacco by reducing the prevalence of smoking. The proposed project will test the impact of nicotine reduction on smoking behavior and smoke exposure in a setting where participants are restricted from using their usual brand cigarettes.
Primary Outcome
Measure of short term smoke exposure, higher scores indicate more smoke exposure. While in the hotel, participants provided breath samples at 8am, 12pm, 4pm, 8pm beginning with 4pm on Day 1 and ending with 12pm on Day 5. Outcome here are from the VLNC condition. Baseline (NNC) data are reported in the baseline characteristics section.
Conditions Studied
Interventions
- OTHER Normal nicotine content cigarettes (NNC, Baseline)
- OTHER Very low nicotine content (VLNC)
Study Locations (1)
South Carolina
- Medical University of South Carolina - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 31 participants |
| Start Date | 2018-04-15 |
| Est. Completion | 2018-12-01 |
| Phase | NA |
What the finished NCT03311646 record still lists
NCT03311646 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 455-participant average among 123 other Smoking trials with a reported enrollment target (93% lower).
The record links to 1 condition, with Smoking appearing as the primary indexed condition, and to 2 interventions - of which Normal nicotine content cigarettes (NNC, Baseline) is the first listed.
NCT03311646 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT03311646 about?
NCT03311646 is a clinical study titled "Impact of Exclusive Use of Low Nicotine Cigarettes on Compensatory Smoking". Smoking is the leading cause of preventable death in the United States. An FDA-mandated reduction in the nicotine content of cigarettes might reduce the health burden of tobacco by reducing the prevalence of smoking. The proposed project will test the impact of nicotine reduction on smoking behavior...
What is the current status of trial NCT03311646?
This trial is currently completed. It is a NA study. The enrollment target is 31 participants. The study started on 2018-04-15. Estimated completion is 2018-12-01.
What conditions does trial NCT03311646 study?
This clinical trial studies the following conditions: Smoking.
What interventions are being tested in trial NCT03311646?
The interventions under investigation include: Normal nicotine content cigarettes (NNC, Baseline) (OTHER), Very low nicotine content (VLNC) (OTHER).
Who is sponsoring clinical trial NCT03311646?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03311646 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Smoking
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03311646's enrollment target sits among peer trials
31 110th of 123 higher than 14 of 123 other Smoking trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Smoking trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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