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ClinicalTrials.gov 6 recruiting now official registry

Chronic Musculoskeletal Pain clinical trials

6 of 14 indexed Chronic Musculoskeletal Pain trials are currently recruiting.

14 US clinical trials · 6 currently recruiting

Chronic Musculoskeletal Pain is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 6 of these trials.

The research picture

Chronic Musculoskeletal Pain has 14 registered US clinical trials, 6 of them open to new participants right now, about 43% of the total.

6
recruiting participants now
43%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
6
top sponsor: VA Office of Research and Development
Phase 21

Active & Recent Trials

14 total, page 1 of 1

RECRUITING NA 216 participants

Group-Based Psychological Treatments Over Video Conference for Older Veterans With Chronic Pain

VA Office of Research and Development

NCT06004804

RECRUITING NA 180 participants

Stepped-Care Intervention of Music and Imagery to Assess Relief (SCIMITAR) Trial

Henry M. Jackson Foundation for the Advancement of Military Medicine

NCT07217821

RECRUITING NA 160 participants

Comparing Single-Session Therapies for Chronic Pain

Mark A. Lumley

NCT07008105

RECRUITING NA 136 participants

The Effect of a Technology-Mediated Integrated Walking and Tai Chi Intervention on Physical Function in Veterans With COPD and Chronic Musculoskeletal Pain

VA Office of Research and Development

NCT05701982

RECRUITING NA 39 participants

This Project is a Three-arm RCT Evaluating Two, Single-session Behavioral Interventions for Adults With Chronic Musculoskeletal Pain (CMP) -- 1) Brief Mindfulness-Oriented Recovery Enhancement (B-MORE) vs. Empowered Relief (ER) -- Relative to the Traditional 8-week Version of MORE.

Florida State University

NCT07193095

RECRUITING NA 10 participants

Pain Disengagement Training (Open Pilot)

Massachusetts General Hospital

NCT06870162

ACTIVE NOT RECRUITING 250 participants

Diagnostic and Prognostic Biomarkers for High-impact Chronic Pain: Development and Validation

Stanford University

NCT04994249

COMPLETED 3,726 participants

Assessing Pain, Patient Reported Outcomes and Complementary and Integrative Health

VA Office of Research and Development

NCT05097521

COMPLETED NA 730 participants

Mission Reconnect-Veterans and Their Partners to Manage Pain and PTSD (MR)

VA Office of Research and Development

NCT03593772

COMPLETED NA 104 participants

University of Michigan / Wayne State Chronic Pain Study

Wayne State University

NCT03391661

COMPLETED Phase 2 40 participants

Krill Oil for Pain in Elders

University of Florida

NCT06580912

COMPLETED NA 37 participants

Pilot Testing A Theory-Driven Self-Management Intervention for Chronic Musculoskeletal Pain

Johns Hopkins University

NCT05020470

COMPLETED NA 23 participants

Neurobiological and Psychological Benefits of Exercise in Chronic Pain and PTSD

VA Office of Research and Development

NCT03283163

COMPLETED 9 participants

BRAIN, Symptoms, and Physical Activity in COPD

VA Office of Research and Development

NCT04291131

Phase Distribution

PhaseTrial count
Phase 2 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Chronic Musculoskeletal Pain Trial Landscape

14 indexed Chronic Musculoskeletal Pain studies · 6 recruiting (43%).

Phase mix: 0 late (III/IV) vs 1 early (I/II).

Top sponsor: VA Office of Research and Development (6 trials), 8 others listed. 14 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Chronic Musculoskeletal Pain?

PlainTrial tracks 14 US clinical trials for Chronic Musculoskeletal Pain, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Chronic Musculoskeletal Pain?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.