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NCT03248375 · ClinicalTrials.gov registry record · NA
Impact of Y90 Radiation Segmentectomy on HCC
A NA study of Hepatocellular Carcinoma, sponsored by Icahn School of Medicine at Mount Sinai.
- Completed
- Registry status
- NA
- Development phase
- 29
- Enrollment target
- 1
- Study location
NCT03248375: Completed NA study of Hepatocellular Carcinoma, sponsored by Icahn School of Medicine at Mount Sinai.
NCT03248375 is a NA study of Hepatocellular Carcinoma that has completed, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 29 participants, below the 257-participant average among 145 other Hepatocellular Carcinoma trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03248375, a NA study of Hepatocellular Carcinoma, has completed, sponsored by Icahn School of Medicine at Mount Sinai.
- COMPLETED
- Registry status
- NA
- Development phase
- 29 participants
- Enrollment target
- 1
- Study location
Study Summary
The aim of this pilot study is to assess the efficacy of radiation segmentectomy with Theraspheres in patients with unresectable hepatocellular carcinoma that would qualify for thermal ablation as per the BCLC guidelines, but are unable to receive thermal ablation due to unfavorable location of target lesions.
Primary Outcome
Efficacy of 90Yttrium (Y90) Radiation Segmentectomy on Unresectable Hepatocellular Carcinoma as measured by tumor response according to mRECIST. CR = Disappearance of any intratumoral arterial enhancement in all target lesions PR = At least a 30% decrease in the diameter of the viable (enhancement in the arterial phase) target lesion SD = Any cases that do not qualify for either partial response or progressive disease PD = An increase of at least 20% in the diameter of viable (enhancing) target
Conditions Studied
Interventions
- RADIATION Radiation Segmentectomy
Study Locations (1)
New York
- Icahn School of Medicine at Mount Sinai - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2016-08-03 |
| Est. Completion | 2021-03-31 |
| Phase | NA |
What the finished NCT03248375 record still lists
NCT03248375 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 257-participant average among 145 other Hepatocellular Carcinoma trials with a reported enrollment target (89% lower).
The record links to 1 condition, with Hepatocellular Carcinoma appearing as the primary indexed condition, and to 1 intervention - of which Radiation Segmentectomy is the first listed.
NCT03248375 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT03248375 about?
NCT03248375 is a clinical study titled "Impact of Y90 Radiation Segmentectomy on HCC". The aim of this pilot study is to assess the efficacy of radiation segmentectomy with Theraspheres in patients with unresectable hepatocellular carcinoma that would qualify for thermal ablation as per the BCLC guidelines, but are unable to receive thermal ablation due to unfavorable location of targ...
What is the current status of trial NCT03248375?
This trial is currently completed. It is a NA study. The enrollment target is 29 participants. The study started on 2016-08-03. Estimated completion is 2021-03-31.
What conditions does trial NCT03248375 study?
This clinical trial studies the following conditions: Hepatocellular Carcinoma.
What interventions are being tested in trial NCT03248375?
The interventions under investigation include: Radiation Segmentectomy (RADIATION).
Who is sponsoring clinical trial NCT03248375?
This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03248375 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hepatocellular Carcinoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03248375's enrollment target sits among peer trials
29 113th of 145 higher than 33 of 145 other Hepatocellular Carcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hepatocellular Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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