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NCT07413250 · ClinicalTrials.gov registry record
Assess Long-Term Safety of Danicopan Add-on Therapy in Participants With Paroxysmal Nocturnal Hemoglobinuria: Analysis of IPIG-Registry Data
A clinical trial of Paroxysmal Nocturnal Hemoglobinuria and PNH, sponsored by Alexion Pharmaceuticals.
- Active
- Registry status
- 50
- Enrollment target
- 1
- Study location
NCT07413250 is a study of Paroxysmal Nocturnal Hemoglobinuria and PNH that is active but no longer recruiting, run by Alexion Pharmaceuticals. The registered enrollment target is 50 participants, below the 261-participant average among 14 other Paroxysmal Nocturnal Hemoglobinuria trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07413250, a study of Paroxysmal Nocturnal Hemoglobinuria and PNH, is active but no longer recruiting, sponsored by Alexion Pharmaceuticals.
- ACTIVE NOT RECRUITING
- Registry status
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a noninterventional registry-based cohort study utilizing data collected on danicopan-treated patients with paroxysmal nocturnal hemoglobinuria (PNH) through the International PNH Interest Group (IPIG) PNH registry. The primary objectives seek to characterize the long-term safety profile of danicopan as add-on therapy to ravulizumab/eculizumab in participants with PNH.
Conditions Studied
Interventions
- DRUG Danicopan
- DRUG Soliris/Ultomiris
Study Locations (1)
Massachusetts
- Clinical Research Site - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2026-01-14 |
| Est. Completion | 2030-01-15 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07413250
The ClinicalTrials.gov registry entry for NCT07413250 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 261-participant average among 14 other Paroxysmal Nocturnal Hemoglobinuria trials with a reported enrollment target (81% lower). The listed sponsor is Alexion Pharmaceuticals, which has 162 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Paroxysmal Nocturnal Hemoglobinuria appearing as the primary indexed condition, and to 2 interventions - of which Danicopan is the first listed.
NCT07413250 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT07413250 about?
NCT07413250 is a clinical study titled "Assess Long-Term Safety of Danicopan Add-on Therapy in Participants With Paroxysmal Nocturnal Hemoglobinuria: Analysis of IPIG-Registry Data". This is a noninterventional registry-based cohort study utilizing data collected on danicopan-treated patients with paroxysmal nocturnal hemoglobinuria (PNH) through the International PNH Interest Group (IPIG) PNH registry. The primary objectives seek to characterize the long-term safety profile of ...
What is the current status of trial NCT07413250?
This trial is currently active not recruiting. The enrollment target is 50 participants. The study started on 2026-01-14. Estimated completion is 2030-01-15.
What conditions does trial NCT07413250 study?
This clinical trial studies the following conditions: Paroxysmal Nocturnal Hemoglobinuria, PNH.
What interventions are being tested in trial NCT07413250?
The interventions under investigation include: Danicopan (DRUG), Soliris/Ultomiris (DRUG).
Who is sponsoring clinical trial NCT07413250?
This trial is sponsored by Alexion Pharmaceuticals, which has 162 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07413250 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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