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NCT06859710 · ClinicalTrials.gov registry record · Phase 1

THC and CBD: A Controlled Human Study Probing a Harm Reduction Strategy

A Phase 1 study of Pain and Abuse, Drug, sponsored by University of California, Los Angeles.

Recruiting
Registry status
Phase 1
Development phase
30
Enrollment target
1
Study location

NCT06859710: Recruiting Phase 1 study of Pain and Abuse, Drug, sponsored by University of California, Los Angeles.

NCT06859710 is a Phase 1 study of Pain and Abuse, Drug that is actively recruiting participants, run by University of California, Los Angeles. The registered enrollment target is 30 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06859710, a Phase 1 study of Pain and Abuse, Drug, is actively recruiting participants, sponsored by University of California, Los Angeles.

RECRUITING
Registry status
Phase 1
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

The purpose of this research is to assess the impact of CBD on the effects of THC.

Primary Outcome

Subject ratings of "Good Drug Effect" as measured using a visual analog scale (1-100 mm)

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG THC
  • DRUG CBD 20 mg
  • DRUG CBD 40 mg
  • DRUG CBD 80 mg

Study Locations (1)

California

  • UCLA Center for Cannabis and Cannabinoids - Los Angeles

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2025-11-05
Est. Completion 2028-09-01
Phase Phase 1

What NCT06859710 shows while recruiting

NCT06859710 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 304-participant average among 374 other Pain trials with a reported enrollment target (90% lower).

The record links to 2 conditions, with Pain appearing as the primary indexed condition, and to 5 interventions - of which Placebo is the first listed.

NCT06859710 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT06859710 about?

NCT06859710 is a clinical study titled "THC and CBD: A Controlled Human Study Probing a Harm Reduction Strategy". The purpose of this research is to assess the impact of CBD on the effects of THC.

What is the current status of trial NCT06859710?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2025-11-05. Estimated completion is 2028-09-01.

What conditions does trial NCT06859710 study?

This clinical trial studies the following conditions: Pain, Abuse, Drug.

What interventions are being tested in trial NCT06859710?

The interventions under investigation include: Placebo (DRUG), THC (DRUG), CBD 20 mg (DRUG), CBD 40 mg (DRUG), CBD 80 mg (DRUG).

Who is sponsoring clinical trial NCT06859710?

This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06859710 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Pain

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06859710's enrollment target sits among peer trials

30 310th of 374 higher than 60 of 374 other Pain trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06859710, the US trial registry maintained by the National Library of Medicine. NCT06859710 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.