Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02558439 · ClinicalTrials.gov registry record · Phase 2
Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Chronic, Moderate to Severe Osteoarthritis Knee Pain
A Phase 2 study of Osteoarthritis, sponsored by Centrexion Therapeutics.
- Completed
- Registry status
- Phase 2
- Development phase
- 175
- Enrollment target
- 20
- Study locations
NCT02558439: Completed Phase 2 study of Osteoarthritis, sponsored by Centrexion Therapeutics.
NCT02558439 is a Phase 2 study of Osteoarthritis that has completed, run by Centrexion Therapeutics. The registered enrollment target is 175 participants, below the 816-participant average among 135 other Osteoarthritis trials with a reported enrollment target (79% lower). The trial reports 20 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02558439, a Phase 2 study of Osteoarthritis, has completed, sponsored by Centrexion Therapeutics.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 175 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to evaluate the safety and efficacy of a single injection of CNTX-4975 in subjects with chronic, moderate to severe osteoarthritis knee pain.
Conditions Studied
Interventions
- OTHER Placebo
- DRUG CNTX-4975
Study Locations (20)
Florida
- Avail Clinical Research, LLC - DeLand
- Finlay Research Clinic - Hialeah
- Eastern Research - Hialeah
- Sunrise Medical Research - Lauderdale Lakes
- M&M Medical Center, Inc - Miami
- Compass Research, LLC - Orlando
- Compass Research, LLC - The Villages
California
- Dream Team Clinical Research, LLC - Anaheim
- Hope Clinical Research, LLC - Canoga Park
- TriWest Research Associates - El Cajon
- BioSolutions Clinical Research Center - La Mesa
- Axis Clinical Trials - Los Angeles
New York
- Drug Trials America - Hartsdale
- Manhattan Medical Research Practice - New York
Alabama
- Achieve Clinical Research, LLC - Birmingham
Arizona
- Advanced Arizona Clinical Research - Tucson
Georgia
- Clinical Research Atlanta - Stockbridge
Missouri
- The Center for Pharmaceutical Research - Kansas City
North Carolina
- Wake Research Associates, LLC - Raleigh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 175 participants |
| Start Date | 2015-08 |
| Est. Completion | 2017-02 |
| Phase | Phase 2 |
What the finished NCT02558439 record still lists
NCT02558439 is an interventional study that assigns participants to a tested intervention. The registered 175 participants enrollment target is mid-sized for trials with a published cap, below the 816-participant average among 135 other Osteoarthritis trials with a reported enrollment target (79% lower).
The record links to 1 condition, with Osteoarthritis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT02558439 names 20 study sites across 9 states, led by Florida, California, New York.
Frequently Asked Questions
What is clinical trial NCT02558439 about?
NCT02558439 is a clinical study titled "Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Chronic, Moderate to Severe Osteoarthritis Knee Pain". The purpose of this study is to evaluate the safety and efficacy of a single injection of CNTX-4975 in subjects with chronic, moderate to severe osteoarthritis knee pain.
What is the current status of trial NCT02558439?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 175 participants. The study started on 2015-08. Estimated completion is 2017-02.
What conditions does trial NCT02558439 study?
This clinical trial studies the following conditions: Osteoarthritis.
What interventions are being tested in trial NCT02558439?
The interventions under investigation include: Placebo (OTHER), CNTX-4975 (DRUG).
Who is sponsoring clinical trial NCT02558439?
This trial is sponsored by Centrexion Therapeutics, which has 12 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02558439 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02558439's enrollment target sits among peer trials
175 66th of 135 higher than 70 of 135 other Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Knee
RECRUITING · Phase 2
-
Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Shoulder
RECRUITING · Phase 2
-
Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Hip
RECRUITING · Phase 2
-
Platelet Rich Plasma Injections In Young And Old Human Subjects
RECRUITING · Phase 2
-
A Mobile Intervention to Reduce Pain and Improve Health-III
RECRUITING · Phase 2
-
An Study to Evaluate Safety and Tolerability of OA-SYS in Subjects With Moderate to Severe Osteoarthritis of the Knee Joint
RECRUITING · Phase 2
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04722341 · 175 participants · NA
Time-Restricted Eating and Cancer: Clinical Outcomes, Mechanisms, and Moderators
- NCT05094037 · 175 participants · NA
Orthotic Treatment of Diabetic Foot Ulcers
- NCT05165745 · 175 participants · NA
Stick2PrEP Cisgender Women and Trans Individuals
- NCT05312255 · 175 participants · NA
Non-chemotherapeutic Interventions for the Improvement of Quality of Life and Immune Function in Patients With Multiple Myeloma
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia