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COMPLETED Phase 2

Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Chronic, Moderate to Severe Osteoarthritis Knee Pain

NCT02558439 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to evaluate the safety and efficacy of a single injection of CNTX-4975 in subjects with chronic, moderate to severe osteoarthritis knee pain.

Conditions Studied

Interventions

  • OTHER Placebo
  • DRUG CNTX-4975

Study Locations (20)

Florida

  • Avail Clinical Research, LLC — DeLand
  • Finlay Research Clinic — Hialeah
  • Eastern Research — Hialeah
  • Sunrise Medical Research — Lauderdale Lakes
  • M&M Medical Center, Inc — Miami
  • Compass Research, LLC — Orlando
  • Compass Research, LLC — The Villages

California

  • Dream Team Clinical Research, LLC — Anaheim
  • Hope Clinical Research, LLC — Canoga Park
  • TriWest Research Associates — El Cajon
  • BioSolutions Clinical Research Center — La Mesa
  • Axis Clinical Trials — Los Angeles

New York

  • Drug Trials America — Hartsdale
  • Manhattan Medical Research Practice — New York

Alabama

  • Achieve Clinical Research, LLC — Birmingham

Arizona

  • Advanced Arizona Clinical Research — Tucson

Georgia

  • Clinical Research Atlanta — Stockbridge

Missouri

  • The Center for Pharmaceutical Research — Kansas City

North Carolina

  • Wake Research Associates, LLC — Raleigh

Trial Details

FieldValue
Enrollment Target 175 participants
Start Date 2015-08
Est. Completion 2017-02
Phase Phase 2

Sponsor

Centrexion Therapeutics

33 total trials

Interested in This Trial?

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02558439

The ClinicalTrials.gov registry entry for NCT02558439 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 175 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Centrexion Therapeutics, which has 33 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Osteoarthritis appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02558439 reports 20 study locations spanning 9 distinct geographic areas — top geographies include Florida, California, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02558439 about?

NCT02558439 is a clinical study titled "Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Chronic, Moderate to Severe Osteoarthritis Knee Pain". The purpose of this study is to evaluate the safety and efficacy of a single injection of CNTX-4975 in subjects with chronic, moderate to severe osteoarthritis knee pain.

What is the current status of trial NCT02558439?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 175 participants. The study started on 2015-08. Estimated completion is 2017-02.

What conditions does trial NCT02558439 study?

This clinical trial studies the following conditions: Osteoarthritis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02558439?

The interventions under investigation include: Placebo (OTHER), CNTX-4975 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02558439?

This trial is sponsored by Centrexion Therapeutics, which has 33 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02558439 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial