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NCT02532244 · ClinicalTrials.gov registry record
Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases
A clinical trial of Amyotrophic Lateral Sclerosis and Spinal Muscular Atrophy, sponsored by Nemours Children's Clinic.
- Completed
- Registry status
- 230
- Enrollment target
- 3
- Study locations
NCT02532244: Completed study of Amyotrophic Lateral Sclerosis and Spinal Muscular Atrophy, sponsored by Nemours Children's Clinic.
NCT02532244 is a study of Amyotrophic Lateral Sclerosis and Spinal Muscular Atrophy that has completed, run by Nemours Children's Clinic. The registered enrollment target is 230 participants, below the 896-participant average among 102 other Amyotrophic Lateral Sclerosis trials with a reported enrollment target (74% lower). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02532244, a study of Amyotrophic Lateral Sclerosis and Spinal Muscular Atrophy, has completed, sponsored by Nemours Children's Clinic.
- COMPLETED
- Registry status
- 230 participants
- Enrollment target
- 3
- Study locations
Study Summary
The goal of this study is to establish a genetic registry of patients with early-onset motor neuron and neuromuscular diseases. The investigators will collect samples from patients with a motor neuron or a neuromuscular disorder and their family members. The samples to be collected will be obtained using minimally invasive (whole blood) means. The research team will then extract high quality genomic DNA or RNA from these samples and use it to identify and confirm novel gene mutations and to identify genes which regulate the severity of motor neuron/neuromuscular diseases.
Primary Outcome
The genetic basis for the subject's condition will be verified/determined by Sanger sequencing of DNA sample
Conditions Studied
Interventions
- OTHER sample collection
Study Locations (3)
Florida
- Nemours Children's Specialty Care - Jacksonville
- Nemours Children's Hospital Orlando - Orlando
Delaware
- Nemours Children's Hospital Delaware - Wilmington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 230 participants |
| Start Date | 2015-06 |
| Est. Completion | 2024-12-18 |
What the finished NCT02532244 record still lists
NCT02532244 is an observational study that tracks outcomes without assigning an intervention. The registered 230 participants enrollment target is mid-sized for trials with a published cap, below the 896-participant average among 102 other Amyotrophic Lateral Sclerosis trials with a reported enrollment target (74% lower).
The record links to 8 conditions, with Amyotrophic Lateral Sclerosis appearing as the primary indexed condition, and to 1 intervention - of which sample collection is the first listed.
NCT02532244 reports a single indexed study location in Florida, Delaware.
Frequently Asked Questions
What is clinical trial NCT02532244 about?
NCT02532244 is a clinical study titled "Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases". The goal of this study is to establish a genetic registry of patients with early-onset motor neuron and neuromuscular diseases. The investigators will collect samples from patients with a motor neuron or a neuromuscular disorder and their family members. The samples to be collected will be obtained ...
What is the current status of trial NCT02532244?
This trial is currently completed. The enrollment target is 230 participants. The study started on 2015-06. Estimated completion is 2024-12-18.
What conditions does trial NCT02532244 study?
This clinical trial studies the following conditions: Amyotrophic Lateral Sclerosis, Spinal Muscular Atrophy, Motor Neuron Disease, Muscular Dystrophy, Charcot Marie Tooth Disease.
What interventions are being tested in trial NCT02532244?
The interventions under investigation include: sample collection (OTHER).
Who is sponsoring clinical trial NCT02532244?
This trial is sponsored by Nemours Children's Clinic, which has 108 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02532244 being conducted?
This trial has 3 study locations across Delaware, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Amyotrophic Lateral Sclerosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02532244's enrollment target sits among peer trials
230 29th of 102 higher than 74 of 102 other Amyotrophic Lateral Sclerosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Amyotrophic Lateral Sclerosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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