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Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases
NCT02532244 · View on ClinicalTrials.gov ↗
Study Summary
The goal of this study is to establish a genetic registry of patients with early-onset motor neuron and neuromuscular diseases. The investigators will collect samples from patients with a motor neuron or a neuromuscular disorder and their family members. The samples to be collected will be obtained using minimally invasive (whole blood) means. The research team will then extract high quality genomic DNA or RNA from these samples and use it to identify and confirm novel gene mutations and to identify genes which regulate the severity of motor neuron/neuromuscular diseases.
Conditions Studied
Interventions
- OTHER sample collection
Study Locations (3)
Florida
- Nemours Children's Specialty Care — Jacksonville
- Nemours Children's Hospital Orlando — Orlando
Delaware
- Nemours Children's Hospital Delaware — Wilmington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 230 participants |
| Start Date | 2015-06 |
| Est. Completion | 2024-12-18 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02532244
The ClinicalTrials.gov registry entry for NCT02532244 describes a study currently listed as completed. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 230 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Nemours Children's Clinic, which has 96 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 8 conditions, with Amyotrophic Lateral Sclerosis appearing as the primary indexed condition, and to 1 intervention — of which sample collection is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT02532244 reports 3 study locations spanning 2 distinct geographic areas — top geographies include Florida, Delaware. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT02532244 about?
NCT02532244 is a clinical study titled "Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases". The goal of this study is to establish a genetic registry of patients with early-onset motor neuron and neuromuscular diseases. The investigators will collect samples from patients with a motor neuron or a neuromuscular disorder and their family members. The samples to be collected will be obtained ...
What is the current status of trial NCT02532244?
This trial is currently completed. The enrollment target is 230 participants. The study started on 2015-06. Estimated completion is 2024-12-18.
What conditions does trial NCT02532244 study?
This clinical trial studies the following conditions: Amyotrophic Lateral Sclerosis, Spinal Muscular Atrophy, Motor Neuron Disease, Muscular Dystrophy, Neuromuscular Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT02532244?
The interventions under investigation include: sample collection (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT02532244?
This trial is sponsored by Nemours Children's Clinic, which has 96 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT02532244 being conducted?
This trial has 3 study locations across Delaware, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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