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NCT07306754 · ClinicalTrials.gov registry record · Phase 1
A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of ABBV-243 in Healthy Adults.
A Phase 1 study of Healthy Volunteers, sponsored by AbbVie.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 66
- Enrollment target
- 1
- Study location
NCT07306754: Recruiting Phase 1 study of Healthy Volunteers, sponsored by AbbVie.
NCT07306754 is a Phase 1 study of Healthy Volunteers that is actively recruiting participants, run by AbbVie. The registered enrollment target is 66 participants, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07306754, a Phase 1 study of Healthy Volunteers, is actively recruiting participants, sponsored by AbbVie.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 66 participants
- Enrollment target
- 1
- Study location
Study Summary
The objective of this study is to assess the safety, tolerability, pharmacokinetics and immunogenicity of either single ascending intravenous (IV) doses of ABBV-243 or single ascending subcutaneous (SC) doses of ABBV-243 in healthy adult participants (Part 1), and a single intravenous (IV) dose in healthy Asian adult volunteers (Part 2 There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires.
Primary Outcome
An AE is defined as any untoward medical occurrence in a patient or clinical investigation subject administered a pharmaceutical product and which does not necessarily have a causal relationship with this treatment.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG ABBV-243
Study Locations (1)
Illinois
- Acpru /Id# 279789 - Grayslake
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 66 participants |
| Start Date | 2025-12-17 |
| Est. Completion | 2027-05 |
| Phase | Phase 1 |
What NCT07306754 shows while recruiting
NCT07306754 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 66 participants, a relatively small participant target, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (86% lower).
The record links to 1 condition, with Healthy Volunteers appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT07306754 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT07306754 about?
NCT07306754 is a clinical study titled "A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of ABBV-243 in Healthy Adults.". The objective of this study is to assess the safety, tolerability, pharmacokinetics and immunogenicity of either single ascending intravenous (IV) doses of ABBV-243 or single ascending subcutaneous (SC) doses of ABBV-243 in healthy adult participants (Part 1), and a single intravenous (IV) dose in h...
What is the current status of trial NCT07306754?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 66 participants. The study started on 2025-12-17. Estimated completion is 2027-05.
What conditions does trial NCT07306754 study?
This clinical trial studies the following conditions: Healthy Volunteers.
What interventions are being tested in trial NCT07306754?
The interventions under investigation include: Placebo (DRUG), ABBV-243 (DRUG).
Who is sponsoring clinical trial NCT07306754?
This trial is sponsored by AbbVie, which has 526 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07306754 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy Volunteers
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07306754's enrollment target sits among peer trials
66 101st of 283 higher than 181 of 283 other Healthy Volunteers trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Volunteers trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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