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NCT02302716 · ClinicalTrials.gov registry record · Phase 3

A Study of LY2963016 Compared to LANTUS® in Adult Participants With Type 2 Diabetes Mellitus

A Phase 3 study of Diabetes Mellitus, Type 2, sponsored by Eli Lilly and Company.

Completed
Registry status
Phase 3
Development phase
493
Enrollment target
20
Study locations

NCT02302716: Completed Phase 3 study of Diabetes Mellitus, Type 2, sponsored by Eli Lilly and Company.

NCT02302716 is a Phase 3 study of Diabetes Mellitus, Type 2 that has completed, run by Eli Lilly and Company. The registered enrollment target is 493 participants, below the 4,484-participant average among 348 other Diabetes Mellitus, Type 2 trials with a reported enrollment target (89% lower). The trial reports 20 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02302716, a Phase 3 study of Diabetes Mellitus, Type 2, has completed, sponsored by Eli Lilly and Company.

COMPLETED
Registry status
Phase 3
Development phase
493 participants
Enrollment target
20
Study locations

Study Summary

The main purpose of this study is to evaluate the safety and efficacy of the study drug known as LY2963016 as compared to LANTUS® in adults with type 2 diabetes mellitus who are on 2 or more oral antihyperglycemic medications (OAMs).

Primary Outcome

HbA1c is the glycosylated fraction of hemoglobin A. HbA1c is measured primarily to identify average plasma glucose concentration over prolonged periods of time. Least Squares (LS) mean was determined by mixed-model repeated measures (MMRM) model with baseline of response, treatment (LY2963016, LANTUS), pooled country, basal insulin at entry (yes/no), sulfonylurea (SU) use (yes/no), visit, treatment and visit\*treatment in the model.

Conditions Studied

Interventions

  • DRUG LY2963016
  • DRUG LANTUS®
  • DRUG Oral Antihyperglycemic Medication

Study Locations (20)

Other

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. - Ahmedabad
  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. - Chennai
  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. - Hyderabad
  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. - Jaipur
  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. - Kormangala
  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. - Mumbai
  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. - New Delhi
  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. - Panjim
  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. - Pune
  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. - Secunderabad

Florida

  • New Horizon Research Center - Miami
  • Suncoast Clinical Research - New Port Richey

Georgia

  • Atlanta Vanguard Medical Associates - Smyrna

Kansas

  • Cotton O'Neil Clinic - Topeka

New York

  • Manhattan Medical Research - New York

Ohio

  • Aventiv Research - Columbus

Tennessee

  • University Diabetes and Endocrine Consultants - Chattanooga

Texas

  • Dallas Diabetes Endocrine Center - Dallas

Trial Details

FieldValue
Enrollment Target 493 participants
Start Date 2014-12
Est. Completion 2016-07
Phase Phase 3
Eli Lilly and Company

1,341 total trials

What the finished NCT02302716 record still lists

NCT02302716 is an interventional study that assigns participants to a tested intervention. The registered 493 participants enrollment target is mid-sized for trials with a published cap, below the 4,484-participant average among 348 other Diabetes Mellitus, Type 2 trials with a reported enrollment target (89% lower).

The record links to 1 condition, with Diabetes Mellitus, Type 2 appearing as the primary indexed condition, and to 3 interventions - of which LY2963016 is the first listed.

NCT02302716 names 20 study sites across 10 states, led by Other, Florida, Georgia.

Frequently Asked Questions

What is clinical trial NCT02302716 about?

NCT02302716 is a clinical study titled "A Study of LY2963016 Compared to LANTUS® in Adult Participants With Type 2 Diabetes Mellitus". The main purpose of this study is to evaluate the safety and efficacy of the study drug known as LY2963016 as compared to LANTUS® in adults with type 2 diabetes mellitus who are on 2 or more oral antihyperglycemic medications (OAMs).

What is the current status of trial NCT02302716?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 493 participants. The study started on 2014-12. Estimated completion is 2016-07.

What conditions does trial NCT02302716 study?

This clinical trial studies the following conditions: Diabetes Mellitus, Type 2.

What interventions are being tested in trial NCT02302716?

The interventions under investigation include: LY2963016 (DRUG), LANTUS® (DRUG), Oral Antihyperglycemic Medication (DRUG).

Who is sponsoring clinical trial NCT02302716?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02302716 being conducted?

This trial has 20 study locations across Florida, Georgia, Kansas, New York, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Diabetes Mellitus, Type 2

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02302716's enrollment target sits among peer trials

493 80th of 348 higher than 269 of 348 other Diabetes Mellitus, Type 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Diabetes Mellitus, Type 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02302716, the US trial registry maintained by the National Library of Medicine. NCT02302716 (mid enrollment · wide site footprint · completed) retrieved and formatted by PlainTrial, see methodology.