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NCT02262325 · ClinicalTrials.gov registry record · Phase 2

Hypofractionated Boost Before Chemoradiation for Patients With Stage II-III Non-small Cell Lung Cancer Unsuitable for Surgery

A Phase 2 study, sponsored by Ohio State University Comprehensive Cancer Center.

Completed
Registry status
Phase 2
Development phase
21
Enrollment target

NCT02262325 is a Phase 2 study that has completed, run by Ohio State University Comprehensive Cancer Center. The registered enrollment target is 21 participants.

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The verdict

NCT02262325, a Phase 2 study, has completed, sponsored by Ohio State University Comprehensive Cancer Center.

COMPLETED
Registry status
Phase 2
Development phase
21 participants
Enrollment target

Study Summary

This phase II trial studies how well giving a hypofractionated boost to the primary tumor before standard chemotherapy and radiation therapy works in treating patients with stage II or III non-small cell lung cancer that cannot be removed by surgery. Advances in radiation oncology have allowed better radiation targeting which may be able to send x-rays directly to the tumor and cause less damage to normal tissue. Drugs used in chemotherapy, such as cisplatin and etoposide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high energy x-rays to kill tumor cells. Giving more precise and targeted radiation before standard chemotherapy and radiation therapy may kill more tumor cells and prevent the cancer from coming back in the location in which it started.

Interventions

  • OTHER laboratory biomarker analysis
  • DRUG cisplatin
  • DRUG etoposide
  • RADIATION hypofractionated radiation therapy
  • RADIATION 3-dimensional conformal radiation therapy

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2015-06-08
Est. Completion 2024-04-15
Phase Phase 2

What the Registry Record Tells You About NCT02262325

The ClinicalTrials.gov registry entry for NCT02262325 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 21 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Ohio State University Comprehensive Cancer Center, which has 341 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which laboratory biomarker analysis is the first listed.

NCT02262325 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02262325 about?

NCT02262325 is a clinical study titled "Hypofractionated Boost Before Chemoradiation for Patients With Stage II-III Non-small Cell Lung Cancer Unsuitable for Surgery". This phase II trial studies how well giving a hypofractionated boost to the primary tumor before standard chemotherapy and radiation therapy works in treating patients with stage II or III non-small cell lung cancer that cannot be removed by surgery. Advances in radiation oncology have allowed bette...

What is the current status of trial NCT02262325?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 21 participants. The study started on 2015-06-08. Estimated completion is 2024-04-15.

What interventions are being tested in trial NCT02262325?

The interventions under investigation include: laboratory biomarker analysis (OTHER), cisplatin (DRUG), etoposide (DRUG), hypofractionated radiation therapy (RADIATION), 3-dimensional conformal radiation therapy (RADIATION).

Who is sponsoring clinical trial NCT02262325?

This trial is sponsored by Ohio State University Comprehensive Cancer Center, which has 341 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.