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NCT02132715 · ClinicalTrials.gov registry record · NA
KAATSU Training to Enhance Physical Function of Older Adults With Osteoarthritis
A NA study of Knee Osteoarthritis, sponsored by University of Florida.
- Completed
- Registry status
- NA
- Development phase
- 35
- Enrollment target
- 1
- Study location
NCT02132715: Completed NA study of Knee Osteoarthritis, sponsored by University of Florida.
NCT02132715 is a NA study of Knee Osteoarthritis that has completed, run by University of Florida. The registered enrollment target is 35 participants, below the 304-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02132715, a NA study of Knee Osteoarthritis, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- NA
- Development phase
- 35 participants
- Enrollment target
- 1
- Study location
Study Summary
As the U.S. population ages and the prevalence of osteoarthritis (OA) among older adults rises, the prevention of OA-associated disability is an important public health priority. Accordingly, efficacious interventions are needed to manage pain and maintain physical function among older adults with OA. Because skeletal muscle weakness is a primary contributory factor to the progression of pain and functional decline among persons with OA, optimal interventions are those capable of improving skeletal muscle strength. High-intensity resistance exercise is the best-known method of improving muscle strength; however high-compressive loads typically induce significant joint pain among persons with OA. Accordingly, current recommendations include the performance of low- or moderate-intensity physical exercise - despite the fact that these training paradigms are sub-optimal for enhancing muscle strength. This application proposes conduct a pilot study to investigate the potential of an innovative training paradigm with potential to stimulate improvements in skeletal muscle strength while utilizing low-intensity loads. This paradigm, known as KAATSU training, involves performing low-intensity exercise while externally-applied compression mildly restricts blood flow to the active skeletal muscle. The overarching objective of the present application is to evaluate the efficacy and feasibility of chronic KAATSU training for the improvement of skeletal muscle strength and physical function among persons aged \> 60 years with symptomatic knee OA and mild to moderate physical limitations. Up to 72 participants will be recruited to participate in this three month intervention study. Participants will be randomly assigned to one of two intervention conditions: (1) a standard exercise intervention consisting of center-based, moderate-intensity resistance training, or (2) a KAATSU training program matched for overall workload. This study will provide novel information regarding the th
Conditions Studied
Interventions
- BEHAVIORAL Resistance Exercise
- BEHAVIORAL KAATSU exercise
Study Locations (1)
Florida
- University of Florida - Gainesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 35 participants |
| Start Date | 2014-09 |
| Est. Completion | 2016-07 |
| Phase | NA |
What the finished NCT02132715 record still lists
NCT02132715 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 35 participants, a relatively small participant target, below the 304-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (88% lower).
The record links to 1 condition, with Knee Osteoarthritis appearing as the primary indexed condition, and to 2 interventions - of which Resistance Exercise is the first listed.
NCT02132715 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT02132715 about?
NCT02132715 is a clinical study titled "KAATSU Training to Enhance Physical Function of Older Adults With Osteoarthritis". As the U.S. population ages and the prevalence of osteoarthritis (OA) among older adults rises, the prevention of OA-associated disability is an important public health priority. Accordingly, efficacious interventions are needed to manage pain and maintain physical function among older adults with O...
What is the current status of trial NCT02132715?
This trial is currently completed. It is a NA study. The enrollment target is 35 participants. The study started on 2014-09. Estimated completion is 2016-07.
What conditions does trial NCT02132715 study?
This clinical trial studies the following conditions: Knee Osteoarthritis.
What interventions are being tested in trial NCT02132715?
The interventions under investigation include: Resistance Exercise (BEHAVIORAL), KAATSU exercise (BEHAVIORAL).
Who is sponsoring clinical trial NCT02132715?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02132715 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Knee Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02132715's enrollment target sits among peer trials
35 78th of 101 higher than 24 of 101 other Knee Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Knee Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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