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NCT01988922 · ClinicalTrials.gov registry record · NA
CYP2B6 Polymorphisms in Ketamine
A NA study of Healthy Volunteers, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT01988922: Completed NA study of Healthy Volunteers, sponsored by Washington University School of Medicine.
NCT01988922 is a NA study of Healthy Volunteers that has completed, run by Washington University School of Medicine. The registered enrollment target is 30 participants, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01988922, a NA study of Healthy Volunteers, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
This research study will determine if genetic variation in CYP2B6 affects how the body metabolizes ketamine.
Primary Outcome
Ketamine metabolism, measured as the plasma norketamine/ketamine AUC ratio in CYP2B6\*6 carriers (CYP2B6\*6 hetero or homozygotes) compared to the wild-type CYP2B6\*1/\*1 genotype Ketamine, norketamine, and dehydronorketamine concentrations in plasma and urine were determined by enantioselective HPLC tandem mass spectrometry, using solid phase extraction, based on a modification of a published method.
Conditions Studied
Interventions
- DRUG ketamine
Study Locations (1)
Missouri
- Washington University School of Medicine - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2013-11 |
| Est. Completion | 2017-05 |
| Phase | NA |
What the finished NCT01988922 record still lists
NCT01988922 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Healthy Volunteers appearing as the primary indexed condition, and to 1 intervention - of which ketamine is the first listed.
NCT01988922 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT01988922 about?
NCT01988922 is a clinical study titled "CYP2B6 Polymorphisms in Ketamine". This research study will determine if genetic variation in CYP2B6 affects how the body metabolizes ketamine.
What is the current status of trial NCT01988922?
This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2013-11. Estimated completion is 2017-05.
What conditions does trial NCT01988922 study?
This clinical trial studies the following conditions: Healthy Volunteers.
What interventions are being tested in trial NCT01988922?
The interventions under investigation include: ketamine (DRUG).
Who is sponsoring clinical trial NCT01988922?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01988922 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01988922's enrollment target sits among peer trials
30 187th of 283 higher than 87 of 283 other Healthy Volunteers trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Volunteers trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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