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NCT05128071 · ClinicalTrials.gov registry record · Early Phase 1
PRevention Of Methamphetamine Use Among Postpartum Women Trial (PROMPT)
A Early Phase 1 study of Methamphetamine-dependence and Postpartum Abstinence, sponsored by University of Utah.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT05128071: Recruiting Early Phase 1 study of Methamphetamine-dependence and Postpartum Abstinence, sponsored by University of Utah.
NCT05128071 is a Early Phase 1 study of Methamphetamine-dependence and Postpartum Abstinence that is actively recruiting participants, run by University of Utah. The registered enrollment target is 40 participants, below the 104-participant average among 18 other Methamphetamine-dependence trials with a reported enrollment target (62% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05128071, a Early Phase 1 study of Methamphetamine-dependence and Postpartum Abstinence, is actively recruiting participants, sponsored by University of Utah.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The PRevention Of Methamphetamine Use among Postpartum Women Trial (PROMPT) is randomized controlled trial of postpartum individuals with methamphetamine use disorder to 12 weeks of 200 mg oral micronized progesterone twice daily or placebo. The aims of this study are to assess the feasibility, safety and preliminary efficacy of micronized progesterone for the prevention of return to methamphetamine use. A secondary aim is to assess participant's salivary levels of allopregnanolone with methamphetamine cravings. This study has the potential to provide effective interventions to prevent methamphetamine use among postpartum women.
Primary Outcome
Recruit and enroll 40 eligible women (postpartum individuals with MUD) in a 15 month period from time of study initiation.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Progesterone
Study Locations (1)
Utah
- University of Utah - Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2022-02-04 |
| Est. Completion | 2027-04 |
| Phase | Early Phase 1 |
What NCT05128071 shows while recruiting
NCT05128071 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 104-participant average among 18 other Methamphetamine-dependence trials with a reported enrollment target (62% lower).
The record links to 2 conditions, with Methamphetamine-dependence appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05128071 reports a single indexed study location in Utah.
Frequently Asked Questions
What is clinical trial NCT05128071 about?
NCT05128071 is a clinical study titled "PRevention Of Methamphetamine Use Among Postpartum Women Trial (PROMPT)". The PRevention Of Methamphetamine Use among Postpartum Women Trial (PROMPT) is randomized controlled trial of postpartum individuals with methamphetamine use disorder to 12 weeks of 200 mg oral micronized progesterone twice daily or placebo. The aims of this study are to assess the feasibility, safe...
What is the current status of trial NCT05128071?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 40 participants. The study started on 2022-02-04. Estimated completion is 2027-04.
What conditions does trial NCT05128071 study?
This clinical trial studies the following conditions: Methamphetamine-dependence, Postpartum Abstinence.
What interventions are being tested in trial NCT05128071?
The interventions under investigation include: Placebo (DRUG), Progesterone (DRUG).
Who is sponsoring clinical trial NCT05128071?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05128071 being conducted?
This trial has 1 study location across Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Methamphetamine-dependence
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05128071's enrollment target sits among peer trials
40 7th of 18 higher than 11 of 18 other Methamphetamine-dependence trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Methamphetamine-dependence trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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