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NCT01659944 · ClinicalTrials.gov registry record · Phase 1

Study to Evaluate the Effect of Eliglustat on the Pharmacokinetics, Safety and Tolerability of Metoprolol in Healthy Adults

A Phase 1 study of Healthy, sponsored by Genzyme, a Sanofi Company.

Completed
Registry status
Phase 1
Development phase
14
Enrollment target
1
Study location

NCT01659944 is a Phase 1 study of Healthy that has completed, run by Genzyme, a Sanofi Company. The registered enrollment target is 14 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01659944, a Phase 1 study of Healthy, has completed, sponsored by Genzyme, a Sanofi Company.

COMPLETED
Registry status
Phase 1
Development phase
14 participants
Enrollment target
1
Study location

Study Summary

The primary objective is to determine the effect of repeated oral doses of eliglustat 150 mg twice daily (BID) on the pharmacokinetics (PK) of orally administered metoprolol 50 mg in healthy adults. The secondary objective is to assess the safety and tolerability of a single oral dose of metoprolol 50 mg when administered alone and in combination with repeated oral doses of eliglustat 150 mg BID in healthy adults.

Conditions Studied

Interventions

  • DRUG Metoprolol
  • DRUG Eliglustat

Study Locations (1)

Texas

  • - Austin

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2012-05
Est. Completion 2012-07
Phase Phase 1

Sponsor

Genzyme, a Sanofi Company

196 total trials

What the Registry Record Tells You About NCT01659944

The ClinicalTrials.gov registry entry for NCT01659944 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 14 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (98% lower). The listed sponsor is Genzyme, a Sanofi Company, which has 196 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which Metoprolol is the first listed.

NCT01659944 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT01659944 about?

NCT01659944 is a clinical study titled "Study to Evaluate the Effect of Eliglustat on the Pharmacokinetics, Safety and Tolerability of Metoprolol in Healthy Adults". The primary objective is to determine the effect of repeated oral doses of eliglustat 150 mg twice daily (BID) on the pharmacokinetics (PK) of orally administered metoprolol 50 mg in healthy adults. The secondary objective is to assess the safety and tolerability of a single oral dose of metoprolol...

What is the current status of trial NCT01659944?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 14 participants. The study started on 2012-05. Estimated completion is 2012-07.

What conditions does trial NCT01659944 study?

This clinical trial studies the following conditions: Healthy.

What interventions are being tested in trial NCT01659944?

The interventions under investigation include: Metoprolol (DRUG), Eliglustat (DRUG).

Who is sponsoring clinical trial NCT01659944?

This trial is sponsored by Genzyme, a Sanofi Company, which has 196 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01659944 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.