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COMPLETED Phase 1

Imaging Regional Lung Defect Severity

NCT01640288 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to develop and evaluate the usefulness of magnetic resonance imaging (MRI) using inert perfluorinated gases mixed with oxygen for regional assessment of pulmonary function. The proposed study seeks to determine regional qualitative and quantitative lung function information in the context of the clinical trajectory of chronic obstructive pulmonary disease (COPD) defined by the cross sectional cohort component. In the case of these perfluorinated (PFx)/oxygen mixtures, the availability of multi-liter quantities allows for wash-in/wash-out image acquisition and analysis allowing direct measures of gas trapping in a manner not easily achieved with any existing modality.

Conditions Studied

Interventions

  • DRUG Perfluorinated Gas/Oxygen Mixture
  • OTHER High Resolution CT of the Chest

Study Locations (1)

North Carolina

  • Duke Image Analysis Laboratory — Durham

Trial Details

FieldValue
Enrollment Target 171 participants
Start Date 2013-01
Est. Completion 2018-08-10
Phase Phase 1

Sponsor

Hal C Charles

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT01640288

The ClinicalTrials.gov registry entry for NCT01640288 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 171 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Hal C Charles, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with COPD appearing as the primary indexed condition, and to 2 interventions — of which Perfluorinated Gas/Oxygen Mixture is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT01640288 reports 1 study location spanning 1 distinct geographic area — top geographies include North Carolina. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT01640288 about?

NCT01640288 is a clinical study titled "Imaging Regional Lung Defect Severity". The purpose of this study is to develop and evaluate the usefulness of magnetic resonance imaging (MRI) using inert perfluorinated gases mixed with oxygen for regional assessment of pulmonary function. The proposed study seeks to determine regional qualitative and quantitative lung function informat...

What is the current status of trial NCT01640288?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 171 participants. The study started on 2013-01. Estimated completion is 2018-08-10.

What conditions does trial NCT01640288 study?

This clinical trial studies the following conditions: COPD. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT01640288?

The interventions under investigation include: Perfluorinated Gas/Oxygen Mixture (DRUG), High Resolution CT of the Chest (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT01640288?

This trial is sponsored by Hal C Charles, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT01640288 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial