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NCT01549652 · ClinicalTrials.gov registry record · NA

5HT3 Antagonists to Treat Opioid Withdrawal and to Prevent the Progression of Physical Dependence

A NA study of Opioid Withdrawal and Physical Dependence, sponsored by Stanford University.

Completed
Registry status
NA
Development phase
133
Enrollment target
1
Study location

NCT01549652 is a NA study of Opioid Withdrawal and Physical Dependence that has completed, run by Stanford University. The registered enrollment target is 133 participants, above the 110-participant average among 9 other Opioid Withdrawal trials with a reported enrollment target (21% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT01549652, a NA study of Opioid Withdrawal and Physical Dependence, has completed, sponsored by Stanford University.

COMPLETED
Registry status
NA
Development phase
133 participants
Enrollment target
1
Study location

Study Summary

Opioid medications are commonly used for pain relief. When given over time, physical dependence can occur. This results in unpleasant side effects (such as agitation and nausea) if opioid medications are suddenly stopped. This study aims to test the use of the drug ondansetron to reduce the symptoms associated with opioid withdrawal and to prevent the progression of opioid physical dependence, thereby allowing future investigators to better test the role of physical dependence in the development of addiction and also possibly improving acceptance of abstinence-based programs for addiction.

Interventions

  • DRUG Placebo
  • DRUG Ondansetron
  • DRUG Morphine
  • DRUG Naloxone 0.4 mg/70 kg
  • DRUG Naloxone 0.8 mg/70 kg

Study Locations (1)

California

  • Stanford University - Stanford

Trial Details

FieldValue
Enrollment Target 133 participants
Start Date 2011-04
Est. Completion 2016-10
Phase NA

Sponsor

Stanford University

1,744 total trials

What the Registry Record Tells You About NCT01549652

The ClinicalTrials.gov registry entry for NCT01549652 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 133 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 110-participant average among 9 other Opioid Withdrawal trials with a reported enrollment target (21% higher). The listed sponsor is Stanford University, which has 1,744 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Opioid Withdrawal appearing as the primary indexed condition, and to 5 interventions - of which Placebo is the first listed.

NCT01549652 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT01549652 about?

NCT01549652 is a clinical study titled "5HT3 Antagonists to Treat Opioid Withdrawal and to Prevent the Progression of Physical Dependence". Opioid medications are commonly used for pain relief. When given over time, physical dependence can occur. This results in unpleasant side effects (such as agitation and nausea) if opioid medications are suddenly stopped. This study aims to test the use of the drug ondansetron to reduce the symptoms...

What is the current status of trial NCT01549652?

This trial is currently completed. It is a NA study. The enrollment target is 133 participants. The study started on 2011-04. Estimated completion is 2016-10.

What conditions does trial NCT01549652 study?

This clinical trial studies the following conditions: Opioid Withdrawal, Physical Dependence.

What interventions are being tested in trial NCT01549652?

The interventions under investigation include: Placebo (DRUG), Ondansetron (DRUG), Morphine (DRUG), Naloxone 0.4 mg/70 kg (DRUG), Naloxone 0.8 mg/70 kg (DRUG).

Who is sponsoring clinical trial NCT01549652?

This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01549652 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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