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NCT05555485 · ClinicalTrials.gov registry record · NA

Understanding the Effects of Transcutaneous Auricular Neurostimulation for Treatment of Chronic Pain

A NA study of Analgesia and Opioid Withdrawal, sponsored by The University of Texas Medical Branch, Galveston.

Recruiting
Registry status
NA
Development phase
60
Enrollment target
1
Study location

NCT05555485 is a NA study of Analgesia and Opioid Withdrawal that is actively recruiting participants, run by The University of Texas Medical Branch, Galveston. The registered enrollment target is 60 participants, below the 90-participant average among 19 other Analgesia trials with a reported enrollment target (33% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05555485, a NA study of Analgesia and Opioid Withdrawal, is actively recruiting participants, sponsored by The University of Texas Medical Branch, Galveston.

RECRUITING
Registry status
NA
Development phase
60 participants
Enrollment target
1
Study location

Study Summary

The purpose of the study is to find out how a stimulation device worn on the ear works. This device is thought to stimulate nerves in the area around the ear to change the signals in the brain. The device has been shown to reduce pain and to reduce the symptoms of withdrawal. The investigator will also investigate changes in the way each participant perceive sensations of pressure and heat. The participant will be asked to reduce the amount of pain medication that they take. Then, the participant will spend several days and nights in the Clinical Research Center at UTMB (University of Texas Medical Branch) in Galveston. During that time, the participant will be monitored for withdrawal symptoms and will receive either active (e.g., "real") brain stimulation or sham (e.g., "fake") brain stimulation for two days (four hours each day). At two times over the course of the study (before and after ear stimulation treatment), the participant will complete questionnaires about their pain score and how they are feeling, sensory testing, and will undergo magnetic resonance imaging (MRI) of their brain. The investigator will collect the following information from the participant's medical record: age, gender, medication history, medical diagnoses, recent vital signs, past doctor visits or hospital stays, and results of urine drug tests. Participation in this study will last approximately four days, and the participant will stay in the Clinical Research Center.

Interventions

  • DEVICE transcutaneous Auricular neurostimulation - Active
  • DEVICE transcutaneous auricular neurostimulation - Sham

Study Locations (1)

Texas

  • University of Texas Medical Branch - Galveston

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2023-05-24
Est. Completion 2027-09-30
Phase NA

What the Registry Record Tells You About NCT05555485

The ClinicalTrials.gov registry entry for NCT05555485 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 90-participant average among 19 other Analgesia trials with a reported enrollment target (33% lower). The listed sponsor is The University of Texas Medical Branch, Galveston, which has 203 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Analgesia appearing as the primary indexed condition, and to 2 interventions - of which transcutaneous Auricular neurostimulation - Active is the first listed.

NCT05555485 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT05555485 about?

NCT05555485 is a clinical study titled "Understanding the Effects of Transcutaneous Auricular Neurostimulation for Treatment of Chronic Pain". The purpose of the study is to find out how a stimulation device worn on the ear works. This device is thought to stimulate nerves in the area around the ear to change the signals in the brain. The device has been shown to reduce pain and to reduce the symptoms of withdrawal. The investigator will a...

What is the current status of trial NCT05555485?

This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2023-05-24. Estimated completion is 2027-09-30.

What conditions does trial NCT05555485 study?

This clinical trial studies the following conditions: Analgesia, Opioid Withdrawal.

What interventions are being tested in trial NCT05555485?

The interventions under investigation include: transcutaneous Auricular neurostimulation - Active (DEVICE), transcutaneous auricular neurostimulation - Sham (DEVICE).

Who is sponsoring clinical trial NCT05555485?

This trial is sponsored by The University of Texas Medical Branch, Galveston, which has 203 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05555485 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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