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NCT01449721 · ClinicalTrials.gov registry record · NA
Preemptive Resuscitation for Eradication of Septic Shock
A NA study of Sepsis and Severe Sepsis, sponsored by Christiana Care Health Services.
- Completed
- Registry status
- NA
- Development phase
- 142
- Enrollment target
- 5
- Study locations
NCT01449721: Completed NA study of Sepsis and Severe Sepsis, sponsored by Christiana Care Health Services.
NCT01449721 is a NA study of Sepsis and Severe Sepsis that has completed, run by Christiana Care Health Services. The registered enrollment target is 142 participants, below the 6,563-participant average among 90 other Sepsis trials with a reported enrollment target (98% lower). The trial reports 5 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01449721, a NA study of Sepsis and Severe Sepsis, has completed, sponsored by Christiana Care Health Services.
- COMPLETED
- Registry status
- NA
- Development phase
- 142 participants
- Enrollment target
- 5
- Study locations
Study Summary
The purpose of this study is to assess the ability of an empiric resuscitation strategy compared to standard care to decrease the incidence of organ failure in normotensive sepsis patients.
Primary Outcome
Development of worsening organ failure defined by the Sequential Organ Failure Assessment (SOFA) score. The SOFA score defines the presence and severity of dysfunction within 6 organ systems (cardiovascular, respiratory, coagulation, liver, renal, and nervous system) with a value of "0" for assigned to normal function to a maximum value of "4" for severe dysfunction in each of the organ systems. Each component of the SOFA score is added together, ranging from "0" indicating no organ dysfunction
Conditions Studied
Interventions
- DRUG Intravenous fluid
Study Locations (5)
Delaware
- Christiana Care Health System - Newark
Massachusetts
- Beth Israel Deaconess Medical Center - Boston
Michigan
- Detroit Receiving Hospital/University Health Center - Detroit
Mississippi
- University of Mississippi Medical Center - Jackson
New Jersey
- Cooper University Hospital:Cooper Medical School of Rowan University - Camden
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 142 participants |
| Start Date | 2011-09 |
| Est. Completion | 2016-01 |
| Phase | NA |
What the finished NCT01449721 record still lists
NCT01449721 is an interventional study that assigns participants to a tested intervention. The registered 142 participants enrollment target is mid-sized for trials with a published cap, below the 6,563-participant average among 90 other Sepsis trials with a reported enrollment target (98% lower).
The record links to 2 conditions, with Sepsis appearing as the primary indexed condition, and to 1 intervention - of which Intravenous fluid is the first listed.
NCT01449721 lists 5 locations in 5 states (Delaware, Massachusetts, Michigan).
Frequently Asked Questions
What is clinical trial NCT01449721 about?
NCT01449721 is a clinical study titled "Preemptive Resuscitation for Eradication of Septic Shock". The purpose of this study is to assess the ability of an empiric resuscitation strategy compared to standard care to decrease the incidence of organ failure in normotensive sepsis patients.
What is the current status of trial NCT01449721?
This trial is currently completed. It is a NA study. The enrollment target is 142 participants. The study started on 2011-09. Estimated completion is 2016-01.
What conditions does trial NCT01449721 study?
This clinical trial studies the following conditions: Sepsis, Severe Sepsis.
What interventions are being tested in trial NCT01449721?
The interventions under investigation include: Intravenous fluid (DRUG).
Who is sponsoring clinical trial NCT01449721?
This trial is sponsored by Christiana Care Health Services, which has 82 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01449721 being conducted?
This trial has 5 study locations across Delaware, Massachusetts, Michigan, Mississippi, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sepsis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01449721's enrollment target sits among peer trials
142 52nd of 90 higher than 39 of 90 other Sepsis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sepsis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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