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Brivanib Alaninate in Treating Patients With Persistent or Recurrent Cervical Cancer
NCT01267253 · View on ClinicalTrials.gov ↗
Study Summary
This phase II trial studies how well brivanib alaninate works in treating patients with cervical cancer that has come back. Brivanib alaninate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth or by blocking blood flow to the tumor.
Conditions Studied
Interventions
- OTHER Laboratory Biomarker Analysis
- DRUG Brivanib Alaninate
Study Locations (20)
Illinois
- Rush University Medical Center — Chicago
- University of Chicago Comprehensive Cancer Center — Chicago
- Sudarshan K Sharma MD Limited-Gynecologic Oncology — Hinsdale
Michigan
- Michigan Cancer Research Consortium NCORP — Ann Arbor
- Saint Joseph Mercy Hospital — Ann Arbor
- Saint Mary Mercy Hospital — Livonia
California
- Providence Saint Joseph Medical Center/Disney Family Cancer Center — Burbank
- UCSF Medical Center-Mount Zion — San Francisco
Connecticut
- Smilow Cancer Hospital Care Center at Saint Francis — Hartford
- The Hospital of Central Connecticut — New Britain
Delaware
- Beebe Medical Center — Lewes
- Christiana Care Health System-Christiana Hospital — Newark
Florida
- Florida Hospital Orlando — Orlando
- Sarasota Memorial Hospital — Sarasota
Maryland
- Greater Baltimore Medical Center — Baltimore
- Union Hospital of Cecil County — Elkton
Arizona
- Saint Joseph's Hospital and Medical Center — Phoenix
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 31 participants |
| Start Date | 2011-04-04 |
| Est. Completion | 2014-02-28 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01267253
The ClinicalTrials.gov registry entry for NCT01267253 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 31 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Gynecologic Oncology Group, which has 61 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 5 conditions, with Cervical Adenocarcinoma appearing as the primary indexed condition, and to 2 interventions — of which Laboratory Biomarker Analysis is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT01267253 reports 20 study locations spanning 11 distinct geographic areas — top geographies include Illinois, Michigan, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT01267253 about?
NCT01267253 is a clinical study titled "Brivanib Alaninate in Treating Patients With Persistent or Recurrent Cervical Cancer". This phase II trial studies how well brivanib alaninate works in treating patients with cervical cancer that has come back. Brivanib alaninate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth or by blocking blood flow to the tumor.
What is the current status of trial NCT01267253?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 31 participants. The study started on 2011-04-04. Estimated completion is 2014-02-28.
What conditions does trial NCT01267253 study?
This clinical trial studies the following conditions: Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Recurrent Cervical Carcinoma, Cervical Squamous Cell Carcinoma, Not Otherwise Specified, Persistent Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT01267253?
The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Brivanib Alaninate (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT01267253?
This trial is sponsored by Gynecologic Oncology Group, which has 61 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT01267253 being conducted?
This trial has 20 study locations across Arizona, California, Connecticut, Delaware, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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