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NCT01267253 · ClinicalTrials.gov registry record · Phase 2

Brivanib Alaninate in Treating Patients With Persistent or Recurrent Cervical Cancer

A Phase 2 study of Cervical Adenocarcinoma and Cervical Adenosquamous Carcinoma, sponsored by Gynecologic Oncology Group.

Completed
Registry status
Phase 2
Development phase
31
Enrollment target
20
Study locations

NCT01267253 is a Phase 2 study of Cervical Adenocarcinoma and Cervical Adenosquamous Carcinoma that has completed, run by Gynecologic Oncology Group. The registered enrollment target is 31 participants, below the 122-participant average among 13 other Cervical Adenocarcinoma trials with a reported enrollment target (75% lower). The trial reports 20 study locations across 11 states.

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The verdict

NCT01267253, a Phase 2 study of Cervical Adenocarcinoma and Cervical Adenosquamous Carcinoma, has completed, sponsored by Gynecologic Oncology Group.

COMPLETED
Registry status
Phase 2
Development phase
31 participants
Enrollment target
20
Study locations

Study Summary

This phase II trial studies how well brivanib alaninate works in treating patients with cervical cancer that has come back. Brivanib alaninate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth or by blocking blood flow to the tumor.

Interventions

  • OTHER Laboratory Biomarker Analysis
  • DRUG Brivanib Alaninate

Study Locations (20)

Illinois

  • Rush University Medical Center - Chicago
  • University of Chicago Comprehensive Cancer Center - Chicago
  • Sudarshan K Sharma MD Limited-Gynecologic Oncology - Hinsdale

Michigan

  • Michigan Cancer Research Consortium NCORP - Ann Arbor
  • Saint Joseph Mercy Hospital - Ann Arbor
  • Saint Mary Mercy Hospital - Livonia

California

  • Providence Saint Joseph Medical Center/Disney Family Cancer Center - Burbank
  • UCSF Medical Center-Mount Zion - San Francisco

Connecticut

  • Smilow Cancer Hospital Care Center at Saint Francis - Hartford
  • The Hospital of Central Connecticut - New Britain

Delaware

  • Beebe Medical Center - Lewes
  • Christiana Care Health System-Christiana Hospital - Newark

Florida

  • Florida Hospital Orlando - Orlando
  • Sarasota Memorial Hospital - Sarasota

Maryland

  • Greater Baltimore Medical Center - Baltimore
  • Union Hospital of Cecil County - Elkton

Arizona

  • Saint Joseph's Hospital and Medical Center - Phoenix

Trial Details

FieldValue
Enrollment Target 31 participants
Start Date 2011-04-04
Est. Completion 2014-02-28
Phase Phase 2

Sponsor

Gynecologic Oncology Group

154 total trials

What the Registry Record Tells You About NCT01267253

The ClinicalTrials.gov registry entry for NCT01267253 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 31 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 122-participant average among 13 other Cervical Adenocarcinoma trials with a reported enrollment target (75% lower). The listed sponsor is Gynecologic Oncology Group, which has 154 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Cervical Adenocarcinoma appearing as the primary indexed condition, and to 2 interventions - of which Laboratory Biomarker Analysis is the first listed.

NCT01267253 reports 20 study locations spanning 11 distinct geographic areas - top geographies include Illinois, Michigan, California.

Frequently Asked Questions

What is clinical trial NCT01267253 about?

NCT01267253 is a clinical study titled "Brivanib Alaninate in Treating Patients With Persistent or Recurrent Cervical Cancer". This phase II trial studies how well brivanib alaninate works in treating patients with cervical cancer that has come back. Brivanib alaninate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth or by blocking blood flow to the tumor.

What is the current status of trial NCT01267253?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 31 participants. The study started on 2011-04-04. Estimated completion is 2014-02-28.

What conditions does trial NCT01267253 study?

This clinical trial studies the following conditions: Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Recurrent Cervical Carcinoma, Cervical Squamous Cell Carcinoma, Not Otherwise Specified, Persistent Disease.

What interventions are being tested in trial NCT01267253?

The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Brivanib Alaninate (DRUG).

Who is sponsoring clinical trial NCT01267253?

This trial is sponsored by Gynecologic Oncology Group, which has 154 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01267253 being conducted?

This trial has 20 study locations across Arizona, California, Connecticut, Delaware, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.