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NCT02921269 · ClinicalTrials.gov registry record · Phase 2

Atezolizumab and Bevacizumab in Treating Patients With Recurrent, Persistent, or Metastatic Cervical Cancer

A Phase 2 study of Cervical Adenocarcinoma and Cervical Adenosquamous Carcinoma, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
11
Enrollment target
20
Study locations

NCT02921269 is a Phase 2 study of Cervical Adenocarcinoma and Cervical Adenosquamous Carcinoma that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 11 participants, below the 123-participant average among 13 other Cervical Adenocarcinoma trials with a reported enrollment target (91% lower). The trial reports 20 study locations across 13 states.

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The verdict

NCT02921269, a Phase 2 study of Cervical Adenocarcinoma and Cervical Adenosquamous Carcinoma, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
11 participants
Enrollment target
20
Study locations

Study Summary

This phase II trial studies how well atezolizumab and bevacizumab work in treating patients with cervical cancer that has come back, remains despite treatment, or has spread to other places in the body. Monoclonal antibodies, such as atezolizumab and bevacizumab, may shrink tumor cell and interfere with the ability of tumor cells to grow and spread.

Interventions

  • DRUG Atezolizumab
  • OTHER Laboratory Biomarker Analysis
  • BIOLOGICAL Bevacizumab

Study Locations (20)

Massachusetts

  • Massachusetts General Hospital Cancer Center - Boston
  • Brigham and Women's Hospital - Boston
  • Beth Israel Deaconess Medical Center - Boston
  • Dana-Farber Cancer Institute - Boston

California

  • Los Angeles County-USC Medical Center - Los Angeles
  • USC / Norris Comprehensive Cancer Center - Los Angeles
  • Keck Medical Center of USC Pasadena - Pasadena

Georgia

  • Emory University Hospital Midtown - Atlanta
  • Emory University Hospital/Winship Cancer Institute - Atlanta

New Jersey

  • Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital - New Brunswick
  • Rutgers Cancer Institute of New Jersey - New Brunswick

Colorado

  • University of Colorado Hospital - Aurora

Florida

  • Moffitt Cancer Center - Tampa

Kentucky

  • University of Kentucky/Markey Cancer Center - Lexington

Maryland

  • Johns Hopkins University/Sidney Kimmel Cancer Center - Baltimore

Trial Details

FieldValue
Enrollment Target 11 participants
Start Date 2017-03-10
Est. Completion 2021-01-13
Phase Phase 2

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT02921269

The ClinicalTrials.gov registry entry for NCT02921269 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 11 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 123-participant average among 13 other Cervical Adenocarcinoma trials with a reported enrollment target (91% lower). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 7 conditions, with Cervical Adenocarcinoma appearing as the primary indexed condition, and to 3 interventions - of which Atezolizumab is the first listed.

NCT02921269 reports 20 study locations spanning 13 distinct geographic areas - top geographies include Massachusetts, California, Georgia.

Frequently Asked Questions

What is clinical trial NCT02921269 about?

NCT02921269 is a clinical study titled "Atezolizumab and Bevacizumab in Treating Patients With Recurrent, Persistent, or Metastatic Cervical Cancer". This phase II trial studies how well atezolizumab and bevacizumab work in treating patients with cervical cancer that has come back, remains despite treatment, or has spread to other places in the body. Monoclonal antibodies, such as atezolizumab and bevacizumab, may shrink tumor cell and interfere ...

What is the current status of trial NCT02921269?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 11 participants. The study started on 2017-03-10. Estimated completion is 2021-01-13.

What conditions does trial NCT02921269 study?

This clinical trial studies the following conditions: Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Recurrent Cervical Carcinoma, Cervical Squamous Cell Carcinoma, Not Otherwise Specified, Stage IV Cervical Cancer AJCC v6 and v7.

What interventions are being tested in trial NCT02921269?

The interventions under investigation include: Atezolizumab (DRUG), Laboratory Biomarker Analysis (OTHER), Bevacizumab (BIOLOGICAL).

Who is sponsoring clinical trial NCT02921269?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02921269 being conducted?

This trial has 20 study locations across California, Colorado, Florida, Georgia, Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.