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RECRUITING Phase 1

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

NCT06618287 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to evaluate the safety, tolerability, drug levels, and preliminary efficacy of BMS-986507 combinations in adult participants with advanced solid tumors.

Interventions

  • DRUG Pembrolizumab
  • DRUG Osimertinib
  • DRUG Nivolumab
  • DRUG Pumitamig
  • DRUG BMS-986507

Study Locations (20)

Ohio

  • Cleveland Clinic — Cleveland
  • Local Institution - 0102 — Columbus

Oregon

  • Local Institution - 0052 — Portland
  • Local Institution - 0090 — Portland

Ontario

  • Local Institution - 0064 — Newmarket
  • Local Institution - 0023 — Ottawa

Alabama

  • University of Alabama at Birmingham — Birmingham

Florida

  • University of Miami Hospital and Clinics, Sylvester Cancer Center — Miami

Illinois

  • Local Institution - 0125 — Maywood

Iowa

  • Local Institution - 0065 — Iowa City

New Jersey

  • John Theurer Cancer Center at Hackensack University Medical Center — Hackensack

Trial Details

FieldValue
Enrollment Target 416 participants
Start Date 2025-02-04
Est. Completion 2031-02-26
Phase Phase 1

Sponsor

Bristol-Myers Squibb

504 total trials

Interested in This Trial?

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06618287

The ClinicalTrials.gov registry entry for NCT06618287 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 416 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Bristol-Myers Squibb, which has 504 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Breast Cancer appearing as the primary indexed condition, and to 5 interventions — of which Pembrolizumab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06618287 reports 20 study locations spanning 17 distinct geographic areas — top geographies include Ohio, Oregon, Ontario. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06618287 about?

NCT06618287 is a clinical study titled "A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors". The purpose of this study is to evaluate the safety, tolerability, drug levels, and preliminary efficacy of BMS-986507 combinations in adult participants with advanced solid tumors.

What is the current status of trial NCT06618287?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 416 participants. The study started on 2025-02-04. Estimated completion is 2031-02-26.

What conditions does trial NCT06618287 study?

This clinical trial studies the following conditions: Breast Cancer, Lung Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06618287?

The interventions under investigation include: Pembrolizumab (DRUG), Osimertinib (DRUG), Nivolumab (DRUG), Pumitamig (DRUG), BMS-986507 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06618287?

This trial is sponsored by Bristol-Myers Squibb, which has 504 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06618287 being conducted?

This trial has 20 study locations across Alabama, Florida, Illinois, Iowa, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial